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294 articles for “Clinical”
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Artificial Intelligence in Nursing: Empowering the Workforce of Tomorrow
Abstract: Artificial Intelligence (AI) is transforming modern healthcare, including nursing practice, by enhancing clinical decision-making, improving patient outcomes, and simplifying administrative tasks. The article also explains the benefits of AI in nursing, such as increased diagnostic accuracy, better time management, and easily accessible mental healthcare for nurses. However, there are drawbacks to using AI, including algorithmic bias, data privacy, moral dilemmas, and the possibility of care disassociation, all which are properly …
Published in International journal of Nursing Science Practice and Research · Vol. 12, Issue 1, 2026 · pp. 6–11 Read article
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Cryogenic Electron Microscopy Reveals Conformational Dynamics and Catalytic Mechanisms of Human Fatty Acid Synthase in De Novo Lipid Biosynthesis
Abstract: Fatty acid synthase (FASN) is a multifunctional homodimeric enzyme central to de novo fatty acid synthesis in mammals. Recent cryogenic electron microscopy (cryo-EM) studies have illuminated the structural basis of FASN catalysis, revealing multiple conformational states throughout the synthesis cycle. These findings show that the acyl carrier protein (ACP) domain dynamically shuttles substrates between spatially separated active sites, while the condensing and modifying regions remain structurally stable. In contrast to …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 8–25 Read article
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Establishment of a Sensitive LC-MS Method for Pharmacokinetic Evaluation of Decitabine and Cedazuridie in Rat Plasma
Abstract: A simple, rapid, and highly sensitive liquid chromatography–mass spectrometry (LC–MS) method was successfully developed and validated for the simultaneous determination of Decitabine and Cedazuridine in plasma matrices. The method demonstrated excellent linearity across the selected calibration range, with correlation coefficients (R²) consistently exceeding 0.999 for both analytes, indicating strong analytical performance. Method validation was carried out in accordance with ICH Q2(R2) and US FDA bioanalytical method validation guidelines, ensuring compliance …
Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 34–42 Read article
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Communication Profile of a Child Suspected to Have Saethre-Chotzen Syndrome: A Case Report
Abstract: Saethre-Chotzen Syndrome (SCS) is a rare congenital craniosynostosis syndrome characterized by craniofacial anomalies, limb abnormalities such as syndactyly, and varying degrees of developmental and cognitive delays. While its genetic and structural features are well-documented, there is limited literature detailing the communication characteristics associated with the condition. This case report describes the comprehensive speech, language, developmental, and auditory profile of an 8-year-old male child presenting with phenotypic features strongly suggestive of …
Published in International Journal of Pediatric Nursing · Vol. 12, Issue 1, 2026 · pp. 14–20 Read article
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Establishment of a Sensitive LC-MS Method for Pharmacokinetic Evaluation of Decitabine and Cedazuridie in Rat Plasma
Abstract: Abstract A simple, rapid, and highly sensitive liquid chromatography–mass spectrometry (LC–MS) method was successfully developed and validated for the simultaneous determination of Decitabine and Cedazuridine in plasma matrices. The method demonstrated excellent linearity across the selected calibration range, with correlation coefficients (R²) consistently exceeding 0.999 for both analytes, indicating strong analytical performance. Method validation was carried out in accordance with ICH Q2(R2) and US FDA bioanalytical method validation guidelines, ensuring …
Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 34–42 Read article
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Advanced Classification of Diabetic Retinopathy Using GAN and Deep Residual CNN Model
Abstract: Diabetic retinopathy (DR) is a leading cause of blindness worldwide, impacting the largest number of individuals who have diabetes. Early identification of diabetic retinopathy may help to prevent severe effects; however, the very limited availability of labeled datasets, and the possibility of overfitting of the model, presents obstacles to obtaining an accurate diagnosis. In this research, a hybrid deep learning strategy is introduced, where Generative Adversarial Networks (GANs) are used …
Published in International Journal of Image Processing and Pattern Recognition · Vol. 12, Issue 1, 2026 · pp. 8–16 Read article
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A Low-Power Chopper-Stabilized Amplifier forHigh-Resolution Biomedical Signal Acquisition
Abstract: Biomedical signal acquisition systems such as ECG, EEG, and EMG require analog front-end (AFE) circuits capable of amplifying extremely small, low-frequency physiological signals in the presence of noise, interference, and motion-induced artifacts. These signals usually fall within the sub-millivolt range and are highly susceptible to low-frequency noise and amplifier offset. Chopper-stabilized amplifiers offer a compelling solution by suppressing flicker noise (1/f noise) and minimizing input- referred offset, especially for low-frequency …
Published in International Journal of Embedded Systems and Emerging Technologies · Vol. 12, Issue 1, 2026 · pp. 1–14 Read article
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Understanding Perceptual Disorders: A Comprehensive Review
Abstract: Perceptual disorders refer to conditions in which a person’s ability to understand sensory information is disturbed, resulting in an altered perception of reality. These disorders affect how individuals experience sensory stimuli such as sight, hearing, touch, taste, and smell. Perceptual disturbances are commonly seen in various psychiatric and neurological conditions and play an important role in influencing a person’s thinking, emotions and behavior. Perceptual disorders mainly occur in the form …
Published in International Journal of Neurological Nursing · Vol. 12, Issue 1, 2026 · pp. 1–6 Read article
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Applications of Bionanocomposites in Healing & Treatment of Tendon & Ligament Injuries.
Abstract: Tendon and tissue injuries are difficult to manage because of their poor natural healing ability and the risk of scar tissue and reinjury. Nanotechnology has created materials that can closely mimic natural biological structures, opening up new possibilities for regenerative medicine in recent years. In the creation of scaffolds and delivery systems for tissue repair, nanomaterials are very useful. The extracellular matrix's nanoscale configuration is replicated using electrospun nanofiber scaffolds, …
Published in International Journal of Composite and Constituent Materials · Vol. 12, Issue 1, 2026 · pp. 17–41 Read article
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Quantum Dots in Oral Diagnostics and Theranostics: Promise and Preclinical Status
Abstract: Quantum dots in oral diagnostics and theranostics represent a rapidly evolving, largely preclinical strategy that couples highly sensitive optical imaging with targeted therapeutic delivery in the oral cavity. Their size-dependent emission, high photostability, and broad excitation spectra allow bright, multiplexed visualization of key molecular events in oral potentially malignant disorders and oral squamous cell carcinoma, while surface functionalization with antibodies, peptides, or smallmolecule ligands enables selective binding to dysplastic and …
Published in International Journal of Applied Nanotechnology · Vol. 12, Issue 1, 2026 · pp. 18–25 Read article
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Smart Hospital Bed System for the Prevention and Management of Bedsores and Pressure Ulcers
Abstract: Pressure ulcers, also known as bed sores, represent a critical challenge in modern healthcare, particularly among immobilized and critically ill patients, leading to increased morbidity, prolonged hospital stays, and higher healthcare costs. Recent advancements in smart healthcare technologies have enabled the development of smart hospital bed systems that integrate sensors, automation, and artificial intelligence to prevent and manage pressure ulcers effectively. These systems incorporate features such as pressure redistribution, automatic …
Published in International Journal of Nursing Critical Care · Vol. 12, Issue 1, 2026 · pp. 1–8 Read article
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Quantum Dots in Oral Diagnostics and Theranostics:Promise and Preclinical Status
Abstract: Quantum dots in oral diagnostics and theranostics represent a rapidly evolving, largely preclinical strategy that couples highly sensitive optical imaging with targeted therapeutic delivery in the oral cavity. Their size-dependent emission, high photostability, and broad excitation spectra allow bright, multiplexed visualization of key molecular events in oral potentially malignant disorders and oral squamous cell carcinoma, while surface functionalization with antibodies, peptides, or small-molecule ligands enables selective binding to dysplastic and …
Published in International Journal of Applied Nanotechnology · Vol. 12, Issue 1, 2026 · pp. 20–30 Read article
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Chemical Engineering Aspects of Carrageenan Hydrogel–Silver Composite Systems: Synthesis, Structure, and Performance
Abstract: This review presents a green chemistry-driven strategy for the synthesis, design, and chemical engineering of carrageenan-based hydrogel matrices embedded with green-synthesized silver nanoparticles (AgNPs) for advanced biomedical and pharmaceutical applications. Silver nanoparticles were fabricated through an environmentally benign route employing natural biopolymeric reducing and stabilizing agents, eliminating the need for hazardous chemical reagents and minimizing ecological impact. The synthesized AgNPs were subsequently incorporated into κ-carrageenan hydrogel networks under controlled physicochemical …
Published in International Journal of Chemical Engineering and Processing · Vol. 12, Issue 1, 2026 · pp. 7–27 Read article
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Chemical Engineering Aspects of Carrageenan Hydrogel–Silver Composite Systems: Synthesis, Structure, and Performance
Abstract: This review presents a green chemistry–driven strategy for the synthesis, design, and chemical engineering of carrageenan-based hydrogel matrices embedded with green-synthesized silver nanoparticles (AgNPs) for advanced biomedical and pharmaceutical applications. Silver nanoparticles were fabricated through an environmentally benign route employing natural biopolymeric reducing and stabilizing agents, eliminating the need for hazardous chemical reagents and minimizing ecological impact. The synthesized AgNPs were subsequently incorporated into κ-carrageenan hydrogel networks under controlled physicochemical …
Published in International Journal of Chemical Engineering and Processing · Vol. 12, Issue 1, 2026 · pp. 7–28 Read article
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Impact of Play-Based Interventions on SeparationAnxiety in Hospitalized Under-Five Children: ASystematic Review
Abstract: Background: Hospitalization in early childhood often triggers significant fear, anxiety, stress, and distress due to parental separation, unfamiliar environments, and medical procedures, which can hinder recovery and emotional stability. Play, a natural mode of self-expression, supports children’s physical, emotional, social, and cognitive development and serves as a non-pharmacological intervention that promotes coping and relaxation. Aim: This systematic review aims to evaluate the efficacy of play-based interventions in reducing separation anxiety …
Published in International Journal of Pediatric Nursing · Vol. 12, Issue 1, 2026 · pp. 1–13 Read article
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A Study to Assess the Effectiveness of Video-Assisted Teaching Program on Knowledge Regarding Prevention of Central Line-Associated Bloodstream Infection (CLABSI) Among Staff Nurses in Dhanvantri Critical Care Centre, Erode
Abstract: Background: A Central Line-Associated Bloodstream Infection (CLABSI) occurs when microorganisms enter a patient’s bloodstream through a central venous catheter. These infections are potentially life-threatening but largely preventable through proper infection control practices. Nurses play a critical role in implementing evidence-based preventive measures to reduce the incidence of CLABSIs. Objectives: The study aimed to evaluate the effectiveness of a video-assisted teaching program in improving staff nurses’ knowledge regarding the prevention of …
Published in International Journal of Nursing Critical Care · Vol. 11, Issue 2, 2025 · pp. 17–27 Read article
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Biopolymers in Medical Application: A Study
Abstract: Biopolymers – naturally derived macromolecules, such as polysaccharides, proteins, and polyhydroxyalkanoates – have emerged as a versatile toolbox for next-generation medical technologies. Their intrinsic biocompatibility, tunable degradation kinetics, and capacity for molecular functionalization enable the design of devices that communicate with living tissue rather than merely coexist with it. This review synthesizes recent advances across four inter-related fronts: (i) drug-delivery carriers, where chitosan-based nanoparticles and hyaluronic-acid hydrogels provide stimulus-responsive release …
Published in International Journal of Polymer Science and Engineering · Vol. 11, Issue 2, 2025 · pp. 1–15 Read article
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Evidence-Based Nursing Care and Quality of Life of Coronary Artery Disease Patients: A Systematic Review
Abstract: Globally, 60% of deaths are attributed to non-communicable diseases (NCDs), which include cardiovascular diseases (CVDs), cancer, chronic respiratory diseases, diabetes, and others. Among these, ischemic heart disease and stroke are the leading causes, collectively accounting for approximately 17.7 million deaths annually. According to the World Health Organization (WHO), India contributes to nearly one-fifth of these deaths, with cardiovascular diseases affecting the Indian population almost a decade earlier compared to their …
Published in International Journal of Medical Surgical Nursing · Vol. 11, Issue 2, 2025 · pp. 19–23 Read article
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A Study to Evaluate the Effectiveness of Standard Operating Nursing Procedures (SONPs) in Reduction of VAPap Among the Patients Admitted in Critical Care Units of SDMSMS & Hospital, Dharwad
Abstract: Background: Nursing is an art & science; nurses are the one who often meet the patients and carried out the nursing procedure to meet the needs of the patient. Ventilator-associated pneumonia in one of the major health concerns associated with a high incidence of mortality and morbidity rate in all the ICUs. There is a need for a proper standard operating nursing procedure to reduce the incidence of VAP to …
Published in International Journal of Medical Surgical Nursing · Vol. 8, Issue 2, 2025 · pp. 21–45 Read article
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A Case Study on Interstitial Lung Diseases (ILD)
Abstract: Interstitial lung diseases (ILDs) represent a diverse group of diffuse parenchymal lung disorders characterized by significant morbidity and mortality worldwide. Recent advances have led to the development of a new classification system for idiopathic interstitial pneumonias, dividing them into major, rare, and unclassified groups, with a novel approach based on disease behavior. Idiopathic pulmonary fibrosis (IPF) remains the most fatal ILD, demonstrating considerable clinical heterogeneity and poor prognosis. Early diagnosis …
Published in International Journal of Medical Surgical Nursing · Vol. 8, Issue 2, 2025 · pp. 13–20 Read article