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16 articles for “target sites”
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A Review Paper on Novel Lipid Nanoparticles for Enhanced Bioavailability of Bioactive Compounds in Breast Cancer Cell Lines
Abstract: Most bioactive compounds from natural products are heavily relied on drug development due to their biological, chemical and pharmacological properties. Some compounds exhibiting anticancer properties have also been reported. However, they present a challenge in achieving the effective absorption and delivery in the body. This is due to minimal bioavailability, fluctuation of plasma drug concentration, low tolerance, first-pass effect which leads to less desired efficacy. Therefore, this calls for an …
Published in International Journal of Composite and Constituent Materials · Vol. 10, Issue 1, 2024 · pp. 1–9 Read article
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Application of Nanotechnology in Food Industry
Abstract: Nanotechnology has the potential of application in the food industry and processing as new tools for pathogen detection, disease treatment delivery systems, food packaging, and delivery of bioactive compounds to target sites.This review is based on the applications of food industry using nanotechnology. The basic categories of nanotechnology applications in the evolution of food Industry includes:Integration of active componentsand improvement of plastic material for packaging of food that conveys useful …
Published in International journal of Nanobiotechnology · Vol. 6, Issue 1, 2020 · pp. 6–12 Read article
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Targeted Drug Delivery and Nanotechnology: An Overview
Abstract: Targeted drug delivery is a special form of drug delivery system where the medicament is selectively delivered or targeted only its site of action and keeping rest part of the body relatively free. Drug is a substance used for prevention, diagnosis, treatment and cure of a disease.Drug and medicine are synonym of each other and commonly used interchangeable. But there is minor difference in between both the terms. Drug is …
Published in International Journal of Composite and Constituent Materials · Vol. 6, Issue 1, 2020 · pp. 34–38 Read article
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Microscopic Avengers: The Rise of Nanorobots in Biomedical Engineering
Abstract: Nanorobotics is an emerging field at the intersection of nanotechnology and robotics, offeringa promising new frontier in biomedical engineering. Nanorobots, at the scale of a fewhundred nanometres, are designed to perform a variety of tasks within the human body,ranging from targeted drug delivery to precise surgical procedures. This article explores theevolution, design, functionality, and applications of nanorobots in biomedical engineering,highlighting their potential to revolutionize healthcare.The evolution of nanorobots has seen …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 9, Issue 2, 2023 · pp. 10–15 Read article
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Protein Peroxidation: The Covalent Modification of Protein Induced Through Reactive Oxygen Species (ROS) and With Secondary By-products of Oxidative Stress.
Abstract: The abundance in biological system and high reaction rate constant are making the proteins as major targets for radicals and two-electron oxidants in biological systems. The multiple side-chain and backbone sites are susceptible for highly reactive radical damage. Less reactive species exhibit greater selectivity with reference to the residues targeted and their spatial location. Modified structure may result in the increased side-chain hydrophilicity, side-chain fragmentation and backbone fragmentation, aggregation through …
Published in International Journal of Chemical Separation Technology · Vol. 5, Issue 2, 2019 · pp. 1–25 Read article
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Appraising Residential Satisfaction Indicators in Emerging Cities of India (Case: Bhopal, Madhya Pradesh)
Abstract: The paper comprises of residential satisfaction parameters. The issue is subjective, as residential satisfaction alters with person to person and surroundings. For convenience we chose cities which were on verge of transformation into metropolitan cities. Research says, residential satisfaction is directly related to housing quality levels i.e. qualitative and quantitative both ways. Quantitatively, residential satisfaction is associated with the cost of living, location, social networks, public transport, and familiarity with …
Published in International Journal of Housing and Human Settlement Planning · Vol. 1, Issue 1, 2015 · pp. 1–8 Read article
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Toxicity Evaluation for accumulation of nanoparticles in biological system
Abstract: Recent years have seen an unprecedented growth in the field of nanotechnology. The application of nanotechnology has risen and now has become a technical necessity in almost every technical field be it medical, therapeutic, cosmetics, agriculture, forensic, defence and many more still to come. Nanotechnology in pharmaceutical application typically involves encapsulation of any drug in “Nano” sized carrier ranging from metallic, polymeric, quantum dots, silicon based, polymeric micelles, liposomes and …
Published in International Journal of Applied Nanotechnology · Vol. 3, Issue 2, 2017 · pp. 1–7 Read article
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Cryogenic Electron Microscopy Reveals Conformational Dynamics and Catalytic Mechanisms of Human Fatty Acid Synthase in De Novo Lipid Biosynthesis
Abstract: Fatty acid synthase (FASN) is a multifunctional homodimeric enzyme central to de novo fatty acid synthesis in mammals. Recent cryogenic electron microscopy (cryo-EM) studies have illuminated the structural basis of FASN catalysis, revealing multiple conformational states throughout the synthesis cycle. These findings show that the acyl carrier protein (ACP) domain dynamically shuttles substrates between spatially separated active sites, while the condensing and modifying regions remain structurally stable. In contrast to …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 8–25 Read article
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Revolutionizing Cancer Treatment through Nanoparticle-Based Drug Delivery Systems
Abstract: Cancer is a leading cause of death worldwide, and the treatment options available have significant limitations, including toxicity, low efficacy, and drug resistance. Nanotechnology has made significant progress in recent years, resulting in the emergence of drug delivery systems based on nanoparticles that are used for cancer treatment. These systems offer numerous benefits, including targeted drug delivery, increased drug stability, and reduced toxicity. Nanoparticle-based drug delivery systems are a promising …
Published in International journal of Nanobiotechnology · Vol. 8, Issue 2, 2022 · pp. 8–15 Read article
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Advancement in Nanodiagnostic for Plant Pathogen Detection
Abstract: Nanotechnology refers to a nanoscale innovation, which has promising applications in everyday life. The word nanotechnology is generally used when referring to materials with the size of 0.1 to 100 nanometers. Nanotechnology is a multi-displinary science involving knowledge fro biology, chemistry, physics and other disciplines. The nanoparticles have small size, large surface area and high reactivity. These properties of nanoparticles revolutionized the agriculture researches. Rapid disease detection, targeted treatments, enhancing …
Published in International journal of Nanobiotechnology · Vol. 4, Issue 2, 2018 · pp. 1–7 Read article
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Advances in Agrochemistry for Sustainable Crop and Soil Management
Abstract: Agrochemistry plays a pivotal role in ensuring sustainable crop production and long-term soil health in the face of increasing global food demand, climate change, and environmental degradation. Conventional agricultural practices, characterized by excessive use of chemical fertilizers and pesticides, have led to soil nutrient imbalance, reduced microbial diversity, and environmental contamination. In response to these challenges, recent advances in agrochemistry have focused on developing sustainable and environmentally friendly approaches for …
Published in International Journal of Agrochemistry · Vol. 12, Issue 1, 2026 · pp. 26–31 Read article
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A Comparative Study of Intravenous Paracetamol and Intravenous Diclofenac for Post-operative Pain Relief
Abstract: Despite advancements reducing mortality rates, adverse effects such as pain, nausea, and vomiting remain prevalent and can hinder recovery. Pain is now considered the fifth vital sign, as defined by the International Association for the Study of Pain, and inadequate pain management can result in prolonged hospital stays, increased drug use, and delayed recovery. Effective postoperative pain control is crucial in preventing respiratory complications and facilitating early discharge and return …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 50–56 Read article
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A Traffic Analysis and Redesign of Transportation Facilities: A Case of Imam Abdullah Bin Saud Road and Khaled Bin Al Walid Street Interchange
Abstract: According to the definition of transportation, a movement of people and goods from one location to another location, we look for transportation facilities to contribute to a smooth traffic movement in a desirable and sustainable manner. Therefore, in case there is any facility which is suffering from chronic congestions, then it is inevitable to consider an improvement of it. The intersection which is located at Imam Abdullah Bin Saud Road …
Published in International Journal of Transportation Engineering and Traffic System · Vol. 5, Issue 1, 2019 · pp. 1–11 Read article
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Influence of Ground Motion Duration on the Peak Drift Demands of Reinforced Concrete Buildings
Abstract: Previous studies regarding the effect of strong-motion duration on the behavior of reinforced concrete buildings indicate that the findings regarding the influence of strong-motion duration on peak damage indicators are not consistent. Most of the previous studies available are based on two dimensional structural models. The objective of the present study is to further investigate the influence of earthquake strong-motion duration on structural behavior with three-dimensional building models. In this …
Published in International Journal of Structural Engineering and Analysis · Vol. 3, Issue 2, 2017 · pp. 35–44 Read article
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Isocoreopsin and Glycogen Phosphorylase – An in-silico Interaction Study: A New Way to Tackle Type 2 Diabetes (T2D)†
Abstract: The activity of glycogen phosphorylase (GP) plays a crucial role in regulating glycogen metabolism, and its excessive activity has been closely linked to the pathogenesis of metabolic disorders, such as type 2 diabetes (T2D). Therefore, targeting GP inhibition has emerged as a significant therapeutic strategy for managing this disease. Current research focuses on the discovery and development of novel small molecules capable of suppressing GP activity. Among these, flavonoids have …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 1, 2025 · pp. 76–80 Read article
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Cost Analysis and Optimization of a Nuclear Assisted Electrolytic Hydrogen Production and Distribution Network in India
Abstract: Hydrogen production by alkaline water electrolysis and its distribution via gas pipelines using nuclear electricity as the energy source is a possible scheme that may help facilitate the adoption and implementation of hydrogen energy systems on a large scale. This work provides a techno-economic assessment of a water cooled nuclear reactor based electrolytic hydrogen production and distribution infrastructure in a developing nation like India. The optimal conditions for electrolysis at …
Published in International Journal of Chemical Engineering and Processing · Vol. 5, Issue 2, 2019 · pp. 23–43 Read article