Search
134 articles for “cancer”
-
Revolutionizing Cancer Treatment through Nanoparticle-Based Drug Delivery Systems
Abstract: Cancer is a leading cause of death worldwide, and the treatment options available have significant limitations, including toxicity, low efficacy, and drug resistance. Nanotechnology has made significant progress in recent years, resulting in the emergence of drug delivery systems based on nanoparticles that are used for cancer treatment. These systems offer numerous benefits, including targeted drug delivery, increased drug stability, and reduced toxicity. Nanoparticle-based drug delivery systems are a promising …
Published in International journal of Nanobiotechnology · Vol. 8, Issue 2, 2022 · pp. 8–15 Read article
-
Advancement of Poly-(ADP – Ribose) Polymerase (PARP) Inhibitors in Cancer Progression and Treatment
Abstract: DNA repair mechanisms are the most common and potential targets in cancer treatment. PARP enzymes play a crucial role in detection of DNA damage and its repair and also in apoptosis. Detailed knowledge of these mechanisms leads to the development of poly-(ADP-Ribose) polymerase (PARP) inhibitors as vigorous anticancer drugs with specific action. PARP inhibitors can selectivity kill tumours with deficiencies in DNA repair proteins like BRCA1/2, exploiting synthetic lethality concept. …
Published in International Journal of Animal Biotechnology and Applications · Vol. 1, Issue 1, 2015 Read article
-
Screening And Docking Studies Of Phytocompounds For Targeting Breast Cancer Receptors And Proteins
Abstract: Phytocompounds, historically endorsed by Ayurveda, have long been recognized for their therapeutic potential in addressing various ailments, including complex diseases. Investigating their efficacy in breast cancer treatment has become a focus of research, employing molecular docking and ADME (Absorption, Distribution, Metabolism, and Excretion) analyses.A study was conducted utilizing 40 selected phytocompounds to assess their impact on various breast cancer receptors and proteins. Molecular docking simulations were performed using iGEMDock and …
Published in International Journal of Animal Biotechnology and Applications · Vol. 9, Issue 2, 2023 · pp. 9–19 Read article
-
A Descriptive Study to Evaluate Knowledge on Cervical Cancer Among Women Aged 25-45 Years in Selected Regions of Punjab
Abstract: The cells that coat the cervix, the lowest portion of the uterus, are where cervical cancer first develops. Disease begins when strong cells on the external layer of the cervix change or get contaminated with human papilloma infection and grow out of control, shaping a mass called tumor. The aim of the study was to assess the knowledge regarding cervical cancer among women of age group between 25-45 years in …
Published in International Journal of Medical Surgical Nursing · Vol. 6, Issue 2, 2023 · pp. 1–5 Read article
-
Level and Pattern of Psychological distress among Family Caregivers of Cancer Patients over the course of chemotherapy and radiation-therapy
Abstract: Introduction: All the phases of cancer trajectory lead to considerable anxiety and pressure for significant others, the treatment phase is stated as the most stressful phase. So the current study is undertaken to understand the pattern of psychological distress among family- caregivers (FCGs) across this crucial period while their loved one were undergoing chemotherapy and/ Radiation-therapy (CT &/RT). Methods: Descriptive, exploratory, longitudinal survey was done to assess the level of …
Published in International journal of Nursing Science Practice and Research · Vol. 4, Issue 2, 2018 · pp. 89–98 Read article
-
Nanotechnology Era: Comprehensive Study of Magnetic ZnxFe2–xO3 Nanoparticles for Enhanced Treatment of Cancer and Infectious Disease
Abstract: In the contemporary world, scientists, technologists, and medical professionals are able to transform the knowledge of nanotechnology to medical treatment. They have been struggling to eradicate or reduce the risk effects of epidemic disease from the world. Such epidemic disease is challenging due to their vast replication, regeneration, hereditary case, genetic variations, and passages through genetic matter. For this reason, this research is focused on the biomedical application of ZnxFe2–xO3 …
Published in International journal of Nanobiotechnology · Vol. 10, Issue 2, 2024 · pp. 33–48 Read article
-
Use of PARP Inhibitor in Cancer Cell Progression
Abstract: DNA damage response (DDR) is the cellular mechanism plays specific role of repairing during genotoxic injuries through specific mechanism of action. The DDR defects involve genomic instability and enhance tumor progression but when molecular alterations occurs in the cells become more susceptible to the pharmacological inhibition of the DNA repairing enzymes.Targeting cellular proteins like poly-ADP-ribose polymerase (PARPs) alters protein structure and function and favors molecular defects of the DDR process …
Published in International Journal of Animal Biotechnology and Applications · Vol. 4, Issue 2, 2018 · pp. 24–35 Read article
-
Evaluation of Cytotoxic Activity of Cestrum nocturnum Leaves Extract against A549 Cell Line using MTT Assay
Abstract: Cancer remains a major global cause of death, necessitating ongoing research for effective treatments. Traditional herbal medicine is being explored for novel anti-cancer compounds. This study investigates the cytotoxic effects of Cestrum nocturnum ethanolic extract on A549 lung cancer cells, a type of non-small cell lung cancer (NSCLC). NSCLC is a significant health concern in India, affecting even non-smokers. Cestrum nocturnum, known as Night-blooming jasmine, has shown promise in inhibiting …
Published in International Journal of Plant Biotechnology · Vol. 9, Issue 2, 2023 · pp. 29–33 Read article
-
A Study to Assess the Effectiveness of Post Mastectomy Exercises on Reduction of Shoulder Pain among Mastectomy Patients in International Cancer Centre, Neyyoor at Kanyakumari District, Tamil Nadu
Abstract: The breast is the emotional symbol of a woman’s pride in her sexuality and motherliness. For many women, mastectomy is a common form of breast cancer treatment, and it constitutes threats to female beauty, sexuality and femininity. Restoration of physical appearance is very important for the women who has undergone mastectomy. The objectives of the study were to assess the pre-test and post-test level of shoulder pain, to find out …
Published in International Journal of Obstetrics, Perinatal and Neonatal Nursing · Vol. 5, Issue 1, 2019 · pp. 46–54 Read article
-
A Review Paper on Novel Lipid Nanoparticles for Enhanced Bioavailability of Bioactive Compounds in Breast Cancer Cell Lines
Abstract: Most bioactive compounds from natural products are heavily relied on drug development due to their biological, chemical and pharmacological properties. Some compounds exhibiting anticancer properties have also been reported. However, they present a challenge in achieving the effective absorption and delivery in the body. This is due to minimal bioavailability, fluctuation of plasma drug concentration, low tolerance, first-pass effect which leads to less desired efficacy. Therefore, this calls for an …
Published in International Journal of Composite and Constituent Materials · Vol. 10, Issue 1, 2024 · pp. 1–9 Read article
-
Predictive Brain Cancer Detection and Treatment Using Machine Learning and Artificial Intelligence
Abstract: Through the combination of Big Data and the computer science discipline of machine learning, significant insights may be gained. Machine learning may now be utilized to anticipate nearly any result based on any capability thanks to developing technology. By analyzing underlying patterns in the data, machine learning creates an appropriate model. Every day, medical sciences must overcome new obstacles, such as patients' lack of knowledge about the ailments they are …
Published in International Journal of Chemical Separation Technology · Vol. 9, Issue 1, 2023 · pp. 28–39 Read article
-
Application of nanotechnology of the effect of an aqueous solution of catholyte on the viability of biological cells and of the effect of an aqueous solution of anolyte on the destruction of cancer cells
Abstract: AbstractNanotechnologies are used in processes occurring in nanometer sizes, at the level of molecules, atoms, ions, etc. The combination of biology, medicine and nanotechnology has led to the emergence of new methods and devices that make it possible to use the chemical, mechanical and other properties of molecules, atoms, ions, as well as to discover new phenomena and biological processes occurring at the molecular, atomic and ionic level. The article …
Published in International Journal of Applied Nanotechnology · Vol. 8, Issue 2, 2022 · pp. 1–14 Read article
-
Human papillomavirus: a review of DNA based therapeutic cancer vaccines routes of administration
Abstract: Human Papillomavirus is the most common sexually transmitted infection. While the virus cancause many negative health effects in both males and females, the most concerning and common ofthese is cervical cancer in females. Immunization is not effective in clearing HPV infection that isalready present. Therefore, there is a need for therapeutic vaccines that work to combat the virusin an individual who has already been exposed and has a persistent infection …
Published in International Journal of Immunological Nursing · Vol. 7, Issue 1, 2021 · pp. 5–13 Read article
-
An Overview on Cannabis and its Medical Applications
Abstract: Today, cannabis plant is raising interest in medical field due to its potential applications, for example, in antitumor drugs, to treat inflammation, cell proliferation, and cell survival. Cannabinoid receptors have a major role in the mechanism of cancer therapy. But in spite of its advantages in medical field, it has some disadvantages also. Due to lack of proper information, it may cause severe side effects. This paper reviews recent work …
Published in International Journal of Plant Biotechnology · Vol. 4, Issue 2, 2018 · pp. 1–5 Read article
-
Fuzzy and Intuitionistic Fuzzy Operators with Applications in Breast Tumor Classification
Abstract: Breast Cancer accounting for 14% of all cancers in women is the most familiar cancer among women in India. According to GLOBOCON data 2018, 1,62,468 new cases and 87,090 demises were accounted for breast cancer in India. The incidence rate of breast cancer starts rising in the early 30s and reaches a peak at the age of 50–64 years. In general, 1 in 28 women will develop breast cancer at …
Published in International Journal of Image Processing and Pattern Recognition · Vol. 9, Issue 1, 2023 · pp. 35–46 Read article
-
Breast Tumor Classification Using Machine Learning Algorithm
Abstract: Breast cancer is characterized by genetic mutations, periodic pain, changes in the length, color (redness) and texture of the breast skin. The categories of most types of breast cancer led the pathologist to a systematic and objective prognostic analysis. In general, the most common category is binary (benign/malignant). Today, Learning Gadget (ML) strategies are widely used in breast cancer classification problems. Offers extreme accuracy and powerful diagnostic technology. It kills …
Published in International Journal of Microwave Engineering and Technology · Vol. 8, Issue 1, 2022 · pp. 35–40 Read article
-
A Study of Segmentation Techniques for Diagnosing Melanoma in Dermoscopic Images
Abstract: Skin cancer remains among the deadliest forms of cancer, with an average survival rate ranging from 18% to 20%. Detecting and segmenting melanoma early is a challenging yet crucial undertaking. To effectively segment the lesions, several studies have presented automated and standard techniques. Likewise, traditional methods for segmentation frequently require inputs from humans and cannot be applied in automated systems. The aim of this article is to provide a comparative …
Published in International Journal of Image Processing and Pattern Recognition · Vol. 10, Issue 1, 2024 · pp. 1–10 Read article
-
Comparative Study of Classification Methods Based on Feature Reduced Microarray Gene-Expression Data
Abstract: Abstract Cancer is a very complex and clinical heterogeneous disease. Now a days the research into the diagnosis and treatment of cancer have become an important issue for researchers. Cancer microarray data normally consist of samples having large number of gene expression as features. For better result in cancer classification it is very important to select relevant features. In this paper, five different types of cancer datasets are used such …
Published in International Journal of Image Processing and Pattern Recognition · Vol. 1, Issue 2, 2015 · pp. 1–10 Read article
-
The Impact of Phytohormones on Human Metabolism and Wellbeing
Abstract: Phytohormones, or plant hormones, are vital organic compounds that regulate plant growth, development, and environmental responses. Recent research has shown that phytohormones like auxins, cytokinin, gibberellins, abscisic acid (ABA), ethylene, brassinosteroids, jasmonates, and salicylic acid may also positively impact human metabolism and overall health. Humans are exposed to these hormones primarily through the consumption of fruits, vegetables, and grains, and emerging studies suggest they may influence human metabolic pathways. This …
Published in International Journal of Plant Biotechnology · Vol. 10, Issue 2, 2024 · pp. 37–48 Read article
-
A Study to assess the Knowledge regarding Breast Self-Examination among Adolescents’ Girls of Govt. Girls Hr. Secondary School, Bairagarh, Bhopal
Abstract: Introduction: Breast cancer is a significant health issue globally, with 1.3 million women diagnosed annually. In India, an estimated 80,000 new cases are diagnosed each year, with 1 in 22 women likely to develop breast cancer. Early detection through breast self-examination (BSE), mammography, and clinical breast exams is crucial. However, awareness is low, especially in rural areas. BSE is a valuable screening tool, allowing women to detect changes and abnormalities. …
Published in International journal of Nursing Science Practice and Research · Vol. 11, Issue 2, 2025 · pp. 1–12 Read article