This survey provides information on( methods of synthesis , reactions , applications in the medical and biological activities , its uses and its source as (whether natural or synthetic) . Chalcones are chemical compounds or natural molecules have a broad spectrum of bio- activities, which are of great interest in many fields. The chemistry of chalcones appeared information about its preparation methods as a starting material in many reactions like cyclization reactions and medical application Keywords : chalcone , cyclization , aldol , medical applications.
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