International Journal of Analytical and Applied Chemistry
Volume 12, Issue 2 (2026)
Table of contents
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Spatial Variation and Pollution Assessment of Selected Water Quality Variables in the Luubara Creek, Niger Delta, Nigeria
Abstract: The spatial variation and pollution status of selected water quality variables in Luubara Creek, Niger Delta, Nigeria, were assessed between June and August 2024. Water samples were collected from four sampling stations, with Stations 1 and 2 representing areas of relatively low anthropogenic influence and Stations 3 and 4 representing areas with greater human activities. Physicochemical parameters and heavy metals were analyzed following the standard methods of the American Public …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 Read article
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Agro Seed Oil Production through Mechanothermal Extraction: Exploring its Potential for Chemical, Pharmaceutical, and Food Industries
Abstract: The increasing demand for sustainable and environmentally friendly industrial raw materials has intensified research into the production of oils from agro seeds using efficient extraction technologies. This study reviews the mechanothermal extraction of agro-seed oils with emphasis on their potential applications in chemical, pharmaceutical, and food industries. Mango (Mangifera indica) seeds, which are commonly discarded as agricultural waste during fruit processing, contain significant quantities of lipids, proteins, carbohydrates, antioxidants, and …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 Read article
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Synthesis, Structural Elucidation, and Antimicrobial Screening of a Cobalt (II) Coordination Compound Derived from a Thiophene-Containing Schiff Base
Abstract: Abstract An N, O-chelating azomethine Schiff base ligand (HL), chemically identified as 2-{[(thiophen-2-yl) methylidene] amino} benzoic acid, was synthesized by an equimolar condensation reaction between thiophene-2-carbaldehyde and anthranilic acid in absolute ethanol in the presence of a catalytic amount of acetic acid. The corresponding cobalt (II) complex, formulated as [Co(L)₂] · 2H₂O, was prepared by refluxing two equivalents of the ligand with one equivalent of cobalt (II) acetate tetrahydrate in …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 1–7 Read article
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Chemistry of Mehandi (Henna): Natural Dyeing Mechanism, Composition, and Applications
Abstract: Mehandi (Henna), derived from the plant Lawsonia inermis, is one of the oldest natural dyes used for body art, hair coloring, and traditional medicinal applications. Beyond its cultural significance, henna represents an interesting example of applied organic chemistry, where naturally occurring molecules interact with biological tissues to produce long-lasting coloration. The primary coloring constituent of henna is Lawsone (2-hydroxy-1,4-naphthoquinone), a naphthoquinone compound responsible for the characteristic reddish-brown stain. When henna …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 39–45 Read article
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Photo-Catalytic Degradation of Dyes Using Graphene Oxide–Dithizone Composite
Abstract: Graphene oxide–dithizone (GO–DTZ) composite was successfully synthesized through the copolymerization of graphene oxide and dithizone to develop an efficient photocatalytic material for wastewater treatment. The dithizone polymer was prepared using a 1:2 molar ratio, while graphene oxide was synthesized via the modified Hummers’ method to obtain highly oxidized graphene sheets with abundant oxygen-containing functional groups. The GO–DTZ nanocomposite was fabricated by ultrasonically dispersing graphene oxide with the synthesized dithizone polymer …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 46–53 Read article
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General and Organic Chemistry Laboratory Experiments for Science, Pre-medical, and Pharmacy Students – Chapter V: Organic Synthesis
Abstract: Organic synthesis can be classified into many types, including simple one-step synthesis, multi-step, one-pot, microwave, or green synthesis. Each type of synthesis takes place through a specific pathway depending on reactants involved, the reaction conditions, the catalyst, the protection group, and the duration of the reaction. In some cases, the required compound can be prepared by more than one procedure, and an expert chemist prefers the procedure by which the …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 8–16 Read article
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Cryogenic Electron Microscopy Reveals Conformational Dynamics and Catalytic Mechanisms of Human Fatty Acid Synthase in De Novo Lipid Biosynthesis
Abstract: Fatty acid synthase (FASN) is a multifunctional homodimeric enzyme central to de novo fatty acid synthesis in mammals. Recent cryogenic electron microscopy (cryo-EM) studies have illuminated the structural basis of FASN catalysis, revealing multiple conformational states throughout the synthesis cycle. These findings show that the acyl carrier protein (ACP) domain dynamically shuttles substrates between spatially separated active sites, while the condensing and modifying regions remain structurally stable. In contrast to …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 8–25 Read article