Hot melt extrusion
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Originative Approaches in Powder Formulation for Enhanced Therapeutic Efficacy
Abstract: Powder formulation is a cornerstone in the pharmaceutical industry, playing a vital role in improving drug efficacy and ensuring optimal therapeutic outcomes. However, traditional formulation methods often face significant challenges, such as poor solubility and low bioavailability, which can limit the effectiveness of many drugs. To address these issues, innovative strategies have emerged, including amorphous solid dispersions (ASDs), nanotechnology, and advanced manufacturing techniques like spray drying and hot melt etrusion. …
Published in International journal of Nanobiotechnology · Vol. 11, Issue 1, 2025 · pp. 1–10 Read article