delocalized π-electrons
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Aromaticity-Guided Synthesis and Reactivity of Heterocyclic Compounds: Structural Insights and Applications
Abstract: The concept of aromaticity serves as a fundamental framework for understanding the structural and electronic characteristics of heterocyclic compounds, which play a crucial role in modern synthetic chemistry. Aromatic compounds, characterized by cyclic planar systems with delocalized π-electrons, follow the Hückel rule, conferring significant stability to heterocyclic structures. The incorporation of heteroatoms, such as nitrogen, oxygen, and sulphur, within these rings profoundly influences electron distribution, molecular reactivity, and synthetic pathways. …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 2, 2026 · pp. 1–7 Read article