chalcone
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Synthesis, Characterization, Chromatographic and Antifungal Evaluation of New Chalcone-Azo Ligand and Complexes
Abstract: Ligand chemistry is fundamental to coordination chemistry, complex chemistry, analytical reagents, andthe treatment of heavy ion pollutants. Recently, ligand complexes have been used in biologicalapplications such as radiation and the treatment of certain types of tumors. Researchers have expandedtheir studies to include complexes such as nanomaterials and drug carriers, demonstrating theireffectiveness through their nanoscale properties. It is worth noting that we chose indole and linked it to achalcone group to …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 1, 2026 · pp. 10–19 Read article
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Synthesis and Evaluation of Antimicrobial Activity of Some Heterocyclic Moieties of Pyrazole Derivatives
Abstract: In a successful trial to synthesize pyrazole derivatives, acetophenone was, first, reacted with phenylhydrazine producing the Schiffs’s base condensation product (E)-1-phenyl-2-(2-phenylethylidene) hydrazine 1. The application of Vilsmeier Haack’s reaction on this product afforded the cyclization product (1,3-diphenyl-1H-pyrazole-4-carbaldehyde 2 as a pyrazole derivative in good yield percentage. The treatment of (1,3-diphenyl-1H-pyrazole-4-carbaldehyde (2) with acetophenone results in the formation of another pyrazole derivative (3), having a chalcone moiety.The chemical structure of newly …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 1, 2025 · pp. 26–36 Read article