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17 articles for “pharmacological applications”
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Therapeutic Potential of Medicinal Pteridophytes in the Doon Valley
Abstract: The Doon Valley, nestled at the foothills of the Himalayas in Uttarakhand, is ecologically rich and biologically diverse. This region, encompassing Dehradun, Mussoorie, and Chakrata, harbors a significant variety of medicinal pteridophytes used in ethnomedicine. These plants, thriving in the region’s subtropical to temperate climate, are integral to traditional healing practices and modern pharmacological applications. A total of 28 medicinal pteridophyte species were identified in this study, each with unique …
Published in International Journal of Plant Biotechnology · Vol. 11, Issue 1, 2025 · pp. 1–19 Read article
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Synthesis and Antifungal Activity of Some Bis-1,4-(3-Mercapto-5-Oxymethyl-1,2,4-Triazole-5-yl) Benzene & Bis-1,4-(5-Amino-2-Oxymethyl-1,3,4-Thiadiazole-2-yl) Benzene
Abstract: Heterocyclic compounds are well known for their pharmacological application. Among all N-containing heterocyclic compounds, triazole emerges superior application. Triazole have two core structures 1,2,4-triazole and 1,2,3-triazoles. They both can give a broad range of substitutions with their structures, due to these characteristics, they have significant biological applications. They are also important in organocatalysis, agrochemicals, and material science. We aim to explore suitable molecular modifications in thiadiazole and triazole derivatives to …
Published in International Journal of Agrochemistry · Vol. 11, Issue 2, 2025 · pp. 9–15 Read article
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Recent Advances in Fused Heterocyclic Pyridine Compounds for Bioactive Anti-Inflammatory Drug Discovery
Abstract: Heterocyclic compounds, particularly those fused with pyridine rings, have emerged as promising candidates in the search for novel bioactive agents with anti-inflammatory properties. This review highlights recent advances in the discovery and development of fused heterocyclic pyridine compounds as potential anti-inflammatory drugs. The unique structural properties of fused heterocycles contribute to their ability to modulate key inflammatory pathways. By targeting specific molecular targets involved in inflammation, such as cytokines, enzymes, …
Published in International Journal of Chemical Separation Technology · Vol. 10, Issue 1, 2024 · pp. 1–7 Read article
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Synthesis of 2-(2,3-dichlorophenyl)-5-(substituted)-1,3,4-Oxadiazole Microcrystals by Solvothermal Method and Assessment of in vitroAntibacterial with Docking and in vivo Larvicidal Efficiency with Comprehensive Toxicological Studies
Abstract: 2,5-Disubstituted 1,3,4-oxadiazole compounds are among the most beneficial organic molecules of biological importance. In the current research, a new series of 2-(2,3-dichlorophenyl)-5-(substituted)-1,3,4-oxadiazole compounds have been synthesized solvothermally from derivatives of2,3-dichloro-N'-(substituted)benzohydrazide and Chloramine-T as an oxidizing agent using autoclave with good yield. The obtained products are micro-sized (5µm–20µm) crystals confirmed through SEM. The structures of synthesized compounds were confirmed through IR, 1H-NMR, 13C-NMR, mass Spectroscopy, Elementary analysis. Molecular docking study shows …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 6, Issue 1, 2020 · pp. 29–44 Read article
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Cold Application Versus Aloe Vera Gel to Reduce Pain, Periorbital Edema, and Ecchymosis Post Craniotomy
Abstract: Background: Craniotomy is a fundamental approach for managing traumatic brain injuries globally. Patients recovering from craniotomy often experience moderate to severe pain, along with periorbital swelling and bruising. Cold therapy and Aloe Vera Gel are non-pharmacological methods that may help alleviate pain and reduce edema after the procedure. The aim of this study is to compare the effectiveness of cold therapy versus Aloe Vera Gel in decreasing pain, periorbital swelling, …
Published in International Journal of Nursing Critical Care · Vol. 10, Issue 2, 2024 · pp. 1–11 Read article
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Nanosuspension-novel Technique for Solubility Enhancement
Abstract: In the treatment of many diseases, getting medicinal compounds to the desired location is a serious issue. Poor biodistribution, limited effectiveness, unfavorable side effects, and a lack of selectivity define traditional medication use. Different types of nanostructures are produced using various size reduction processes and technologies, each with its own set of physicochemical and biological features. These technologies make nanostructures a good material for biomedical applications, and they've gained a …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 7, Issue 2, 2021 · pp. 18–24 Read article
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Bacterial Exopolysaccharides and Their Applications: A Short Review
Abstract: Extracellular polymer substances (EPS) are metabolic products of bacteria which accumulate on thecell surface and serve as a protective layer against harsh environmental condition. EPS also serve asa source of energy during the starvation of bacteria. The major structural component of EPS ispolysaccharide, commonly known as exopolysaccharide, is either neutral or polyanionic in nature.Polysaccharides in EPS found different in sugar compositions and moieties, chain length, repeatingunits and substitutions in the …
Published in International Journal of Analytical and Applied Chemistry · Vol. 7, Issue 1, 2021 · pp. 40–46 Read article
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A Study to Assess the Effectiveness of Local Cold Application Prior to Intramuscular Injection for Reducing Needle Stick Pain among the Patients in Selected Hospitals at Amritsar
Abstract: INTRODUCTION: Pain is highly unpleasant and very personal sensation. It is not just a physical feeling. It affects on one’s attitude and personality. The world is full of unexplained pain, has many possible causes. All persons either Infants or adults have pain during their life time from different reasons, it may be due to any injury or any infection. For the treatment of said causes they needs medical attention but …
Published in International Journal of Nursing Critical Care · Vol. 5, Issue 2, 2019 · pp. 48–54 Read article
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A Comprehensive Review On Pharmacological Activities And Clinical Impacts Of Myristica Fragrans(Nutmeg).
Abstract: Numerous herbal medicines have been used in various medical systems to treat and control a variety of ailments. Myristica fragrans is a perennial spice species that belongs to the Myristicaceae family. It has been cultivated all throughout the world and is used to flavor food, make essential oils, and in traditional remedies. Mostly terpenes and phenyl propenes are found in nutmeg and it is a critical component in a wide …
Published in International Journal of Plant Biotechnology · Vol. 8, Issue 2, 2022 · pp. 12–21 Read article
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Review on Preparation and Application Fields of Triazole &Tetrazole Derivatives
Abstract: This review described triazole and tetrazole (five-ring), these are heterocyclic aromatic five-ring compounds consisting of (two carbon atoms and three nitrogen atoms in triazole) while (four nitrogen atoms with one carbon atom in terazole), and they exist in three different formulas with different locations of heterogeneous atoms in the ring. These compounds were distinguished by a high efficiency towards microorganisms and microbes and have wide importance in the field of …
Published in International Journal of Analytical and Applied Chemistry · Vol. 6, Issue 1, 2020 · pp. 35–45 Read article
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Effectiveness of Icepack Application on Reduction of Labour Pain Among Primi Gravid Women During First Stage of Labour Admitted in MGMCRI
Abstract: Pain is a highly unpleasant and very personal sensation that cannot be shared with others. Normally labour pain in primi mothers is unbearable, usually they cry out for help when the intensity increases. Many non pharmacologic methods relieve labour pain. Many women appreciate the simplicity of these methods to reduce labour pain without creating potentially serious side effects or high economic costs. The objectives of the study were to assess …
Published in International Journal of Obstetrics, Perinatal and Neonatal Nursing · Vol. 3, Issue 2, 2017 · pp. 1–5 Read article
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The effectiveness of medical antibiotics and herbs as antibiotic on mouth bacterial flora
Abstract: BackgroundPlant are the oldest source of pharmacological active compounds. The Achyranthes aspera's seeds, roots and shoots are used as medicine from ancient times. Oral infections and oral disease are directly depends on the oral application of our daily lives. The present study gives information on anti-bacterial properties of this plant. The role of this plant against bacteria have been screened and confirmed by many researchers.While many people in the villages …
Published in International journal of Nursing Science Practice and Research · Vol. 7, Issue 2, 2021 Read article
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Mirror to Review of Lumpy Skin Disease
Abstract: Lumpy Skin Disease (LSD) is a disorder which is affecting most of the animals and thus is spreading to nations worldwide and is becoming as an epidemic in current times and serves as a platform to turn attention towards its rising disorder. It is a carrier spread disease transmitted by different arthropods. This article provides detailed information about the LSD, LSDV, and diagnosis (not by regular blood tests but using …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 2, 2024 · pp. 16–24 Read article
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Assessing the Impact of Foot Massage on Pain Reduction in Patients After Cardiothoracic Surgery
Abstract: In the United States, it is stated that cardiac surgery can result in various sources of pain. Inevitably, there is pain associated with the wound, and beyond the sternotomy incision, there may be an extensive leg wound from vein harvesting. Other contributors to pain and discomfort include drains in the mediastinal and pleural regions, tracheal tubes, and urethral catheters. Activities such as physiotherapy, movement, and tracheal toileting (suctioning of secretions) …
Published in International Journal of Medical Surgical Nursing · Vol. 7, Issue 1, 2024 · pp. 1–7 Read article
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A Comprehensive Review on Withania somnifera Species
Abstract: Withania somnifera (L.) Dunal, often referred to as Ashwagandha or Indian ginseng, is a renownedmedicinal herb widely utilized in traditional medical practices, especially Ayurveda, and it belongs tothe Solanaceae family. The plant has attracted considerable scientific interest because of its wide rangeof pharmacological effects and therapeutic possibilities. Different sections of this plant, particularly theroots and leaves, possess bioactive components that enhance its therapeutic properties. Many experimental and clinical studies have …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 12, Issue 1, 2026 Read article
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Study of the Effect of SLS Loading on the One-Pot Synthesis of Substituted Piperidines
Abstract: Piperidine derivatives represent a vital class of nitrogen-containing heterocycles with extensive pharmacological and industrial significance. Their synthesis has garnered considerable interest due to their presence in numerous bioactive molecules, including drugs with CNS activity, analgesic properties, and antimicrobial effects. Traditional multi-step synthetic pathways are often time-consuming and resource-intensive. To address this, one-pot multicomponent reactions (MCRs) have emerged as an efficient and eco-friendly alternative, allowing for the rapid construction of complex …
Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 1–9 Read article
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EFFECT OF MUSIC THERAPY ON ANXIETY AMONG PATIENTS IN INTENSIVE CARE UNIT
Abstract: BackgroundAn intensive care unit is a special department of a hospital or health care facility that provides intensive care to patients with severe or life-threatening illnesses and injuries, which require constant care, close supervision from life support equipment and medication in order to ensure normal bodily functions. Anxiety is common among intensive care unit patients which can lead to various physiological and psychological changes making the patient recovery difficult. Effective …
Published in International Journal of Nursing Critical Care · Vol. 8, Issue 1, 2022 · pp. 11–18 Read article