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7 articles for “oxadiazole”
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Heterocyclic Oxadiazole Derivatives Through Various Spectroscopic Techniques as UV, IR.
Abstract: The study focuses on the synthesis, characterization, and analysis of heterocyclic oxadiazole derivatives using various spectroscopic techniques, including UV-visible (UV-Vis) spectroscopy and infrared (IR) spectroscopy. Oxadiazoles are a type of five-membered heterocyclic compounds with nitrogen and oxygen atoms. They are important in medical chemistry and materials research and show a wide range of biological activity. The synthesized oxadiazole derivatives were characterized through UV-Vis spectroscopy to investigate their electronic transitions and …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 1, 2024 · pp. 1–8 Read article
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Different Method for the Production of OxadiazoleCompounds
Abstract: The creation of procedures for the environmentally friendly synthesis of materials and chemicals isreferred to as "green synthetic protocol." The synthesis of different biologically active compounds isdone through energy-efficient and environmentally safe processes like microwave irradiationtechnology, ultrasound-mediated synthesis, photo-catalysis (ultraviolet, visible, and infraredirradiation), molecular sieving, grinding, and milling techniques, etc. These procedures are regardedas sustainable technology and have gained value as green protocols for the synthesis of novelmedicinal compounds because …
Published in International Journal of Chemical Engineering and Processing · Vol. 10, Issue 1, 2024 · pp. 20–26 Read article
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Synthesis of 2-(2,3-dichlorophenyl)-5-(substituted)-1,3,4-Oxadiazole Microcrystals by Solvothermal Method and Assessment of in vitroAntibacterial with Docking and in vivo Larvicidal Efficiency with Comprehensive Toxicological Studies
Abstract: 2,5-Disubstituted 1,3,4-oxadiazole compounds are among the most beneficial organic molecules of biological importance. In the current research, a new series of 2-(2,3-dichlorophenyl)-5-(substituted)-1,3,4-oxadiazole compounds have been synthesized solvothermally from derivatives of2,3-dichloro-N'-(substituted)benzohydrazide and Chloramine-T as an oxidizing agent using autoclave with good yield. The obtained products are micro-sized (5µm–20µm) crystals confirmed through SEM. The structures of synthesized compounds were confirmed through IR, 1H-NMR, 13C-NMR, mass Spectroscopy, Elementary analysis. Molecular docking study shows …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 6, Issue 1, 2020 · pp. 29–44 Read article
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The Study of Activity of Heterocyclic Oxadiazole Derivatives and It’s Application’s
Abstract: Due to their biological actions, oxyadiazole derivatives are a significant class of heterocyclics that havegenerated a lot of interest in designing and synthesizing them. Oxadiazole is a heterocyclic substancethat can be made from a 5-member ring that contains nitrogen and oxygen. The development of thesynthetic chemical oxadiazole demonstrates the biological activity. The goal of this review is to gatherinformation on the creation of Oxadiazole derivatives and the functions they serve. …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 9, Issue 1, 2023 · pp. 1–10 Read article
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REVIEW ON PREPARATION METHODS & APPLICATION FIELDS OF OXADIAZOLE
Abstract: This review displays oxadiazole (five-ring) that is of great importance in the fields of pharmacy, medicine, and field of coordinated chemistry and as reagents to estimate the small quantities of trace elements and minerals. Oxadiazole is a primary role and as a basic substance for many pharmacokinetic compounds such as antimalarial drugs, anti- bacterial, and cancerous tumors. This survey described several approach for preparation methods of oxadizole with their applications …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 6, Issue 1, 2020 · pp. 49–60 Read article
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Advance in the Synthesis of Oxadiazole Based Heterocyclic Compound
Abstract: The five members of the heterocyclic ring 1,3,4-oxadiazole are necessary for the production of strong bioactive molecules. Numerous pharmacological effects, including anti-inflammatory, antibacterial, anticancer, antitubercular, anticonvulsant, anti-HIV, hypoglycemic, and antioxidant qualities, are exhibited by this intriguing class of chemicals. We have created four novel 1,3,4-oxadiazole compounds in the continuing study, which are sourced from the NSAID Ibuprofen. Melting point analysis and TLC were used to verify the compounds' purity. Open …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 9, Issue 2, 2023 · pp. 10–15 Read article
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COMPLEXATION AND ANTIBACTERIAL STUDY OF 1,3,4-OXADIAZOLE DERIVATIVE
Abstract: New metal complexes of Zn(II),and Ni(II) have been synthesized by reacting metal solutions with the ligand 2,5-substituted 1,3,4-Oxadiazoles in alcoholic medium. Molecular formulae of the complexes were determined and are further characterized by IR spectroscopy, magnetic susceptibility and molar conductance studies. Since two nitrogen atoms coordinate to the metal center, the ligand is termed as bidentate ligand.KEY WORDS: Complexes, Ligands, Transition metal complexes, Oxadiazoles.
Published in International Journal of Green Chemistry · Vol. 6, Issue 2, 2020 · pp. 26–29 Read article