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47 articles for “ligand”
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Synthesis, Characterization, Chromatographic and Antifungal Evaluation of New Chalcone-Azo Ligand and Complexes
Abstract: Ligand chemistry is fundamental to coordination chemistry, complex chemistry, analytical reagents, andthe treatment of heavy ion pollutants. Recently, ligand complexes have been used in biologicalapplications such as radiation and the treatment of certain types of tumors. Researchers have expandedtheir studies to include complexes such as nanomaterials and drug carriers, demonstrating theireffectiveness through their nanoscale properties. It is worth noting that we chose indole and linked it to achalcone group to …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 1, 2026 · pp. 10–19 Read article
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Synthesis and Biological Evaluation of a Novel Schiff Base Ligand [(E)-2,4-Dichloro-6-(1-((4-Fluorophenyl) iminoethyl)phenol] and Its Metal Complexes
Abstract: The study involved the synthesis and characterization of a novel bidentate Schiff base ligand, [(E)-2,4-dichloro-6-(1-((4-fluorophenyl) iminoethyl) phenol)], derived from 1-(3,5-dichloro-2-hydroxyphenyl) ethanone and 4-fluoroaniline. Transition metal salts (Co (II), Cu (II), Fe (II), Zn (II), Ni (II), Mn (II), Ag (II), Cd (II), Hg (II), and Pd (II)) were used to synthesize metal complexes. The chemicals used were of analytical grade, and solvents were distilled before use. Characterization involved UV, IR, …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 1, 2024 · pp. 26–35 Read article
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Thermogravimetic Study Of Chrysodine Dye Type Bridge Containing Bis (8-quinolinol)s Ligands and Their Coordination Polymers
Abstract: Our thermogravimetric analysis state that the degradation in chrysodine dye type bridge containing bis (8-quinolinol)s metal coordination polymers was initiated at almost the same temperature near about 25-500 C(T0). The remarkable difference is observed in the mode of thermal degradation of the parent ligand and its coordination polymer. The unchelated bis(8-quinolinol) ligand and coordination polymers begin to decompose almost at the same temperature but in the polymer chelates this decomposition …
Published in International Journal of Composite Materials and Matrices · Vol. 9, Issue 2, 2023 · pp. 32–40 Read article
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A Study of Thermodynamics of Ligand - Receptor Interaction in Chemical Sciences
Abstract: The formation and separation of definite non-covalent interactions between varieties of macromolecules play a crucial role in the function of biological systems. During the last few years, three main lines of research led to a dramatic improvement of our understanding of these important phenomena. First, combination of genetic engineering and X ray crystallography made available a simultaneous knowledge of the precise structure and affinity of series or related ligand-receptor systems …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 3, Issue 2, 2017 · pp. 12–16 Read article
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Synthesis, Spectral Study, SEM Analysis and Antibacterial Study of New Indole Azo Ligand and Complexes
Abstract: Azo ligands have developed significantly in recent decades due to their fundamental role in the coordination chemistry of transition elements. Their rapid response to coordination bonding in ligand and complex chemistry, particularly with divalent ions, is a key factor. The azo-bridged bond has played a well-established role in the formation of cobalt, nickel, and copper complexes. In this study, we prepared a novel ligand, an indole derivative bonded to an …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 12, Issue 1, 2026 · pp. 1–10 Read article
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SYNTHESIS AND IR-SPECTROSCOPIC STUDY OF MIXED LIGAND COMPLEX COMPOUNDS OF COPPER (II) FORMAT WITH SOME AMIDES
Abstract: Complex compounds of metals with amides, having biological activity are widely used in agriculture. Complex compounds of copper with organic ligands are physiologically active, participating in the vital processes of living organisms; the formiats have bactericidal and fungicidal properties. For the first time, mixed ligand complex compounds of copper (II) formate with formamide, thiocarbamide, acetamide and carbamide in an aqueous solution were synthesized. Using the methods of IR spectroscopy and …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 6, Issue 2, 2020 · pp. 31–38 Read article
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Synthesis and Characterization of Mixed Ligand Complexes of Hydroxamic Acids with Metal (II) Phthalimide
Abstract: The mixed ligand complexes of Co (II) and Ni (II) with potassium salt of phthalimide (primary ligand) and hydroxamic acids (secondary ligand), where hoxm = L1=3,4,5-trimethoxy benzohydroxamic acids (TMBHA), L2=N-phenyl–3,4,5-trimethoxy benzohydroxamic acid (PTMBHA), L3=3,4-di methoxy benzohydroxamic acid (DMBHA) and L4=N-phenyl-3,4-di methoxy benzohydroxamic acid (PDMBHA) and phth=phthamlimide were synthesized and characterized by elemental analysis, melting points, I.R studies, UV–visible analysis, measurement of magnetic susceptibility, thin layer chromatography, etc. Elemental analysis depicts …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 3, Issue 1, 2017 · pp. 1–6 Read article
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Preparation and Characterization of Mixed Ligand Complexes of Cobalt(II) and Ni(II) salt of Phthalimide with Some Oxamic Acids
Abstract: The mixed ligand complexes of oxamic acids with Co(II) and Ni(II) salt of phthalimide were prepared, where oxm= N-phenyl thio urea oxamic acid(NPTUOA),m-tolumide oxamic acid (m-TOA), N-pyrrazole oxamic acid & phth= Co(II) and Ni(II) salt of phthamlimide. These all mixed ligand complexes examined by their elemental analysis, melting points, UV-visible analysis, I.R studies, magnetic susceptibility measurements and thin layer chromatography. Elemental analysis of the complexes shows 1:2 (Metal:Ligand) stiochiometry for …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 3, Issue 1, 2017 Read article
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Reactivity of Niobium(V) ComplexTowards Hydroxamate Ligands
Abstract: A niobium(V) complex with the composition [NbCl(OC₆H₄CH(CH₃)₂-2)₄] was synthesized by reacting niobium pentachloride with four equivalents of 2-isopropylphenol in carbon tetrachloride as a solvent, yielding the product in good quantity. The complex was characterized using elemental analysis, molar conductance measurements, IR spectroscopy, ¹H and ¹³C NMR spectroscopy, and mass spectrometry. Spectroscopic results indicate that the complex exists in a dimeric form, with bridging occurring through isopropylphenoxo ligands. X-ray diffraction analysis …
Published in International Journal of Energetic Materials · Vol. 12, Issue 1, 2026 · pp. 1–6 Read article
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Synthesis, Spectral and Magnetic Moment Studies of Mixed Ligand Complexes of Hydroxamic Acids with Potassium Hexathiocyanato Vanadium (II) Tetra Hydrate
Abstract: Preparation and characterization of several hydroxamic acids of 3,4,5-trimethoxy benzohydroxamic acids(TMBHA), N-phenyl–3,4,5-trimethoxy benzohydroxamic acid(PTMBHA), 3,4-dimethoxy benzohydroxamic acid(DMBHA) and N-phenyl-3,4-dimethoxy benzohydroxamic acid(PDMBHA) were prepared and reacted with potassium hexathiocynato vandate (II) K4[V(NCS)6].3H2O tetra hydrate. The mixed ligand complexes of hydroxamic acids characterized with the help of repeated melting point identification, by I.R. studies, magnetic moment, molar conductance’s and by elemental analysis (C, H and N). The geometry of complexes were found …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 2, Issue 2, 2016 Read article
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SYNTHESIS AND CHARACTERIZATION OF MIXED LIGAND COMPLEXES OF HYDROXAMIC ACIDS WITH POTASSIUM HEXATHIOCYANATO CHROMIUM (III) TETRA HYDRATE
Abstract: Some hydroxamic acids eg.[L1= benzohydroxamic acids (BHA), L2= N-phenyl– benzohydroxamic acid (NPBHA), L3= pivaloyl benzohydroxamic acid (PHA) and L4=N-phenyl-pivaloyl benzohydroxamic acid (PPHA) prepared and reacted with L’=Potassium hexathiocynato chromium (III) tetra hydrate K3[Cr(SCN)6]4H2O.The mixed ligand complexes of hydroxamic acids characterized with the help of repeated melting point, by I.R. studies, magnetic moment, molar conductance and by elemental analysis(C,H and N).The stoichiometry of the complexes were found to be 1:2(M:L) molar …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 2, Issue 2, 2016 Read article
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Synthesis, Structural Elucidation, and Antimicrobial Screening of a Cobalt (II) Coordination Compound Derived from a Thiophene-Containing Schiff Base
Abstract: Abstract An N, O-chelating azomethine Schiff base ligand (HL), chemically identified as 2-{[(thiophen-2-yl) methylidene] amino} benzoic acid, was synthesized by an equimolar condensation reaction between thiophene-2-carbaldehyde and anthranilic acid in absolute ethanol in the presence of a catalytic amount of acetic acid. The corresponding cobalt (II) complex, formulated as [Co(L)₂] · 2H₂O, was prepared by refluxing two equivalents of the ligand with one equivalent of cobalt (II) acetate tetrahydrate in …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 1–7 Read article
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COMPLEXATION AND ANTIBACTERIAL STUDY OF 1,3,4-OXADIAZOLE DERIVATIVE
Abstract: New metal complexes of Zn(II),and Ni(II) have been synthesized by reacting metal solutions with the ligand 2,5-substituted 1,3,4-Oxadiazoles in alcoholic medium. Molecular formulae of the complexes were determined and are further characterized by IR spectroscopy, magnetic susceptibility and molar conductance studies. Since two nitrogen atoms coordinate to the metal center, the ligand is termed as bidentate ligand.KEY WORDS: Complexes, Ligands, Transition metal complexes, Oxadiazoles.
Published in International Journal of Green Chemistry · Vol. 6, Issue 2, 2020 · pp. 26–29 Read article
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Anti-tubercular activity of dioxo molybdenum (VI) metal complexes of 2-((E)-(1,5-dimethyl-2-phenyl-3-((Z)-(quinoline-8-ylimino)methyl)-2,3-dihydro-1H-pyrazole-4-ylimino)methyl)phenol
Abstract: Dioxomolybdenum(VI) complexes tetradentate ligand 2-((E)-(1,5-dimethyl-2-phenyl-3-((Z)-(quinoline-8-ylimino)methyl)-2,3-dihydro-1H-pyrazole-4-ylimino)methyl)phenol was synthesized by conventional method The ligands and their MoO22+ complexes have been characterized on the basis of elemental analysis, electronic. I.R., 1H and 13C-NMR spectral method, by their spectral studies, octahedral geometry of the complex has been proposed. On evaluation of in-vitro antitubercular activity of the ligand and dioxo Mo(VI) metal complex found that complex is more potent antitubercular agent than ligand. Keywords: anti-tubercular …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 3, Issue 1, 2017 Read article
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Synthesis, characterization of Schiff base and its pH metrically studies of transition metal complexes of N'-(3, 4-dihydroxybenzylidene) isonicotinohydrazide.
Abstract: Schiff reaction is one of the versatile reaction widely used in organic synthesis focused on the discovery & development of isoniazide Schiff base derivative N’(3,4-Dihydroxy benzylidene isonicotinohydrazide) have been reported in presence of 0.01g molecular iodine catalyst stirring give fast product & good yield. The synthesized compound is characterized by FTIR & H-NMR analysis. For the development of coordination chemistry Schiff base & metal ion having played most important role, …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 6, Issue 2, 2020 · pp. 39–47 Read article
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Synthesis, Characterization and Catalytic Study of Chitosan-Schiff Base Manganese Complex
Abstract: Schiff base is the condensation product formed when a primary amine reacts with a carbonyl compound. The term Schiff base is normally applied to those compounds when they are being used as ligands to form coordination complexes with metal ions. Its formation takes place under acid or base catalysis or with heat. Vanillin Schiff base and Aspartic acid-Salicylaldehyde Schiff bases have been synthesised bycondensation reaction. The synthesized ligands were mixed …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 8, Issue 1, 2022 · pp. 1–6 Read article
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Syenthesis characterization and biological activities of Schiff base metal complexes of Zr (II) Ba(II), Cu(II), Sr(II) and Th (II) derived from sulfa pyridine
Abstract: Abstract : The Schiff base ligand was prepared by sulfapyridine with salicylaldehyde Zr(II), Ba(II), Co(II), Sr(II) and Th (II) complexes of above ligand was synthesized as well. The synthesized complexes have been characterized by powder XRD and SEM. The anti microbial activity of synthesized ligand ant its complexes have been tested for their antibacterial activity against bacterial species, such as Bacillus subtilis, staphylococcus aureus, Pseudomonas, aeruginosa, Enterobacter aerogenes, E-coli and …
Published in International Journal of Polymer Science and Engineering · Vol. 5, Issue 1, 2019 · pp. 30–37 Read article
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In silico evaluation for the repurposing of antiviral drugs towards multiple targets of monkey pox viral disease
Abstract: Objective: Monkeypox is a growing public health problem. The disease is caused by the monkeypox virus. The latest epidemic has been linked to previously unknown mutations and variations. Tecovirimat is a poxvirus medication that has been licenced by the US Food and Drug Administration (FDA). Otherwise, there is little pharmacopoeia and scientific interest inmonkeypox. Computational screening and molecular interactions were used in this work to investigate the possible repurposing of …
Published in International Journal of Animal Biotechnology and Applications · Vol. 9, Issue 1, 2023 · pp. 22–32 Read article
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A New Multidentate Fluorescent Chemosensor for metal ions: Synthesis and Fluorescence Response
Abstract: We report the synthesis and the fluorescence response to metal ions of a multidentate pyridyl-based ligand in MeCN/H2O (3/7) solution. The ligand was synthesided via overnight refluxing of a ethanolic mixture of 2,6-diamino pyridine and di(pyridine-2-yl)methanone. studies reveal the ligand display sensing response ability in the presence of certain metal ions. It display significant fluorescent quenching in the presence of Ni2+, Co2+, Zn2+ and Cd2+, with remarkable fluorescence “turn-off” response …
Published in International Journal of Environmental Chemistry · Vol. 5, Issue 1, 2019 · pp. 10–17 Read article
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ISONIAZID STABILIZED TUNGSTEN TRICARBONYL COMPLEX: A NEW CO-RELEASING MOLECULE WITH ANTIBACTERIAL ACTIVITY
Abstract: Transition metal carbonyl complexes substituted with biologically active ligand can act as CO-releasing molecules which have beneficial roles including antimicrobial activity. Careful choices of ancillary ligand such as isoniazid help in eliminating issues of toxicity that may arise from drug substrates. Substitution reaction of tungsten hexacarbonyl with isoniazid in the presence of trimethylamine N-oxide under nitrogen atmosphere was carried out at ambient temperature for 72 hrs. The product was characterized …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 5, Issue 1, 2019 · pp. 36–43 Read article