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111 articles for “Substitution”
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Natural Polymers as Substitutes for Gelatine Capsules: A Comprehensive Overview
Abstract: Gelatine capsules are widely used in the pharmaceutical and nutraceutical industries for over a century due to their easy-to-swallow nature and their ability to release pharma active ingredients in a controlled manner. However, due to growing concerns over health, ethical issues, and environmental issues associated with the use of animal-derived products, there has been a significant interest towards developing natural, plant-based, and synthetic alternatives to gelatine. This article briefly explores …
Published in International Journal of Polymer Science and Engineering · Vol. 11, Issue 1, 2025 · pp. 9–13 Read article
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Synthesis of 2-(2,3-dichlorophenyl)-5-(substituted)-1,3,4-Oxadiazole Microcrystals by Solvothermal Method and Assessment of in vitroAntibacterial with Docking and in vivo Larvicidal Efficiency with Comprehensive Toxicological Studies
Abstract: 2,5-Disubstituted 1,3,4-oxadiazole compounds are among the most beneficial organic molecules of biological importance. In the current research, a new series of 2-(2,3-dichlorophenyl)-5-(substituted)-1,3,4-oxadiazole compounds have been synthesized solvothermally from derivatives of2,3-dichloro-N'-(substituted)benzohydrazide and Chloramine-T as an oxidizing agent using autoclave with good yield. The obtained products are micro-sized (5µm–20µm) crystals confirmed through SEM. The structures of synthesized compounds were confirmed through IR, 1H-NMR, 13C-NMR, mass Spectroscopy, Elementary analysis. Molecular docking study shows …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 6, Issue 1, 2020 · pp. 29–44 Read article
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Study of the Effect of SLS Loading on the One-Pot Synthesis of Substituted Piperidines
Abstract: Piperidine derivatives represent a vital class of nitrogen-containing heterocycles with extensive pharmacological and industrial significance. Their synthesis has garnered considerable interest due to their presence in numerous bioactive molecules, including drugs with CNS activity, analgesic properties, and antimicrobial effects. Traditional multi-step synthetic pathways are often time-consuming and resource-intensive. To address this, one-pot multicomponent reactions (MCRs) have emerged as an efficient and eco-friendly alternative, allowing for the rapid construction of complex …
Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 1–9 Read article
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Performance Enhancement of Cold Mix Asphalt via FlyAsh Substitution: Marshal Stability Results
Abstract: This study examines the enhancement of cold mix asphalt (CMA) performance through the substitution of fly ash at varying percentages. Specifically, Marshal stability tests were conducted on CMA mixtures with fly ash content of 0%, 2.5%, 5%, and 7.5%. The results reveal a significant increase in peak loads, with the CMA mixture containing no fly ash achieving a peak load of 0.62 kN, while mixtures with 2.5%, 5%, and 7.5% …
Published in International Journal of Polymer Science and Engineering · Vol. 10, Issue 1, 2024 · pp. 16–21 Read article
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Diesel Engine Combustion and Emission Characteristics Study, Taking into Account the Potential of Biogas Substitution for the Purpose of Enhancing Environmental Cleanliness and Promoting Health
Abstract: Necessity for alternative fuels arises from the escalating energy requirements and the detrimental effects of fossil fuel emissions on environmental well-being. Alternative fuels have been extensively researched to improve energy efficiency. A study examines how alternative fuel affects compression ignition (CI) engine performance, pollution, and combustion. Biogas is investigated as a diesel engine fuel substitute in this study using computational fluid dynamics (CFD). Upon doing a thorough examination of the …
Published in International Journal of I.C. Engines and Gas Turbines · Vol. 9, Issue 1, 2023 · pp. 24–39 Read article
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Utilizing Ground Granulated Blast Furnace Slag (GGBS)as a Partial Substitute for Cement in Concrete
Abstract: Abstract Concrete is a critical material in civil engineering, valued for its strength and durability. However, the increasing demand for concrete, driven by rapid urbanization, has raised environmental concerns.Cement, a primary component of concrete, is a significant source of carbon dioxide emissions duringits production, contributing to climate change and environmental degradation. This study investigatesa sustainable alternative to traditional cement by partially replacing it with Ground Granulated BlastFurnace Slag (GGBS), an …
Published in International Journal of Concrete Technology · Vol. 11, Issue 1, 2025 · pp. 28–33 Read article
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Chemical Treatments to Modify the Surface of Agricultural Waste Fibers as a Green Substitute to Cellulosic Fiber Treatment
Abstract: Scientists are searching for natural elements that can decompose naturally and replace synthetic materials that have not been biodegradable for a while. The automotive, space, furniture, construction, medical, and packaging industries are among the many that use synthetic composite materials. This has resulted in growing interest in biodegradable bio composites. In recent years, a variety of stem fibers, including jute, flax, hemp, and kenaf, have been employed to replace the …
Published in International Journal of Composite and Constituent Materials · Vol. 11, Issue 1, 2025 · pp. 35–45 Read article
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A Randomized Controlled Trial to Evaluate the Impact of Heparin Saline and 0.9% Sodium Chloride on Maintaining Central Venous Catheter Patency in Critically Ill Patients at PGIMS, Haryana
Abstract: Background: Central venous catheters (CVCs) are frequently utilized in healthcare environments, especially within intensive care units (ICUs), for various medical purposes. They are inserted to facilitate the delivery of fluids, blood products, medications, parenteral nutrition, as well as for monitoring central venous pressure and performing dialysis. Objectives: The main objective of the study was to assess the effectiveness of heparin saline compared to 0.9% sodium chloride in ensuring the patency …
Published in International Journal of Nursing Critical Care · Vol. 11, Issue 1, 2025 Read article
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Isocoreopsin and Glycogen Phosphorylase – An in-silico Interaction Study: A New Way to Tackle Type 2 Diabetes (T2D)†
Abstract: The activity of glycogen phosphorylase (GP) plays a crucial role in regulating glycogen metabolism, and its excessive activity has been closely linked to the pathogenesis of metabolic disorders, such as type 2 diabetes (T2D). Therefore, targeting GP inhibition has emerged as a significant therapeutic strategy for managing this disease. Current research focuses on the discovery and development of novel small molecules capable of suppressing GP activity. Among these, flavonoids have …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 1, 2025 · pp. 76–80 Read article
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Mechanical Behavior of Calotropis Gigantea FruitBunch Fiber-Epoxy Composites
Abstract: Global warming solutions in the modern era are centered on substituting environmentally friendly biodegradable materials for fossil fuels to slow down the rate at which they are being depleted. The study literature supports the use of substitute materials for plastics in the creation of composite materials, and this work envisions the use of Calotropis gigantea fruit bunch fiber as one such substitute material. Since Calotropis gigantea fruit bunch fiber is …
Published in International Journal of Composite Materials and Matrices · Vol. 10, Issue 2, 2024 · pp. 45–58 Read article
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ISONIAZID STABILIZED TUNGSTEN TRICARBONYL COMPLEX: A NEW CO-RELEASING MOLECULE WITH ANTIBACTERIAL ACTIVITY
Abstract: Transition metal carbonyl complexes substituted with biologically active ligand can act as CO-releasing molecules which have beneficial roles including antimicrobial activity. Careful choices of ancillary ligand such as isoniazid help in eliminating issues of toxicity that may arise from drug substrates. Substitution reaction of tungsten hexacarbonyl with isoniazid in the presence of trimethylamine N-oxide under nitrogen atmosphere was carried out at ambient temperature for 72 hrs. The product was characterized …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 5, Issue 1, 2019 · pp. 36–43 Read article
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Magnetic Field Guided Diluted Magnetic Semiconductor, ZnxFe2-xO3 Nanoparticles for Biomedical and Biosensing Application
Abstract: The magnetic field guided nanoparticles are studied in the viewpoint of diluted magnetic semiconductor. Different structures and properties associated with Zn doped αFe2O3 nanostructures are presented in theoretical formulations. In addition, scientific methods of synthesizing particularly Solvothermal and biological methods of synthesizing Zn0.6Fe1.6O3 nanoparticles are discussed. More emphasis is given to the essence of nanotechnology from non-organic to organic matter namely nanoparticles of Zn0.6Fe1.6O3 to DNA. For in vivo or …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 8, Issue 1, 2022 · pp. 1–18 Read article
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An Article on Partial Fulfillment of Coarse Aggregate in Concrete Mix
Abstract: AbstractBakelite, a synthetic thermosetting polymer, has been extensively utilized in the production of variouscomponents across different industries in India. As the demand for Bakelite continues to rise, so doesthe challenge of managing its waste, which poses significant environmental concerns due to its nonbiodegradable nature. In this context, utilizing Bakelite waste as a partial substitute for coarseaggregate in concrete presents an innovative and environmentally sustainable approach to wastemanagement. This method not …
Published in International Journal of Concrete Technology · Vol. 10, Issue 2, 2024 · pp. 1–5 Read article
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BAYESIAN ANALYSIS OF BIRD OVOMUCOID: INFERRING EVOLUTIONARY DYNAMICS AND PHYLOGENETIC RELATIONSHIPS.
Abstract: Objective: Ovomucoid is a serine protease inhibitor discovered in bird eggs that not only protects embryos but also has phylogenetic significance due to its potential usage as a molecular marker. They are glycoproteins that have antibacterial efficacy because they inhibit bacterial proteolytic enzymes that are essential for microbiological development. This study makes use of DNA sequence data to rebuild evolutionary connections among bird species. Methods: Over the past decade, the …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 1, 2024 · pp. 1–10 Read article
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BAYESIAN ANALYSIS OF BIRD OVOMUCOID: INFERRINGEVOLUTIONARY DYNAMICS AND PHYLOGENETIC RELATIONSHIPS.
Abstract: Objective: Ovomucoid is a serine protease inhibitor discovered in bird eggs that not only protects embryo but also has phylogenetic significance due to its potential usage as a molecular marker. They are glycoproteins that have antibacterial efficacy because they inhibit bacterial proteolytic enzymes that are essential for microbiological development. This study makes use of DNA sequence data to rebuild evolutionary connections among bird species.Methods: Over the past decade, the incorporation …
Published in International Journal of Animal Biotechnology and Applications · Vol. 10, Issue 1, 2024 Read article
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Review of Partial Replacement of Cement with Metakaolin and Utilization of M-Sand, Alongside Addition of Steel Fiber, in the Construction Industry
Abstract: In this contemporary context, demands placed on concrete have escalated significantly. Variousessential properties of concrete such as strength, durability, workability, and expected service liferequire enhancement. This work focuses on investigating the strength properties of concrete throughdifferent substitutions of cement with metakaolin (MK), manufactured sand (M-sand), and steel fiber.Tests were conducted in accordance with Bureau of Indian Standards guidelines to assess thesuitability of MK as a cement replacement. Steel fiber was …
Published in International Journal of Construction Engineering and Planning · Vol. 10, Issue 1, 2024 · pp. 26–30 Read article
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Analyzing Strength Properties of Self-Compacting Concrete at Elevated Temperatures
Abstract: This study investigates the influence of fly ash substitution for Ordinary Portland Cement (OPC) on the compressive and splitting tensile strengths of Self-Compacting Concrete (SCC) mixes. The findings reveal that while early age strength may decrease with fly ash substitution, strategic material selection, such as incorporating foundry sand, mitigates this decline. Satisfactory fresh properties were achieved across SCC mixes labeled SCC1-SCC4, with compressive strengths ranging from 30.49 to 19.19 MPa …
Published in International Journal of Concrete Technology · Vol. 10, Issue 1, 2024 Read article
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Parametric Analysis and Optimization of Nuclear Assisted Electrolytic Hydrogen Production System for On-site Applications
Abstract: The use of compact water electrolyser units as an alternative source of hydrogen to the high pressure hydrogen cylinder banks used at present in nuclear and thermal power reactors for turbo-generator rotor cooling applications has been analysed in this work. Financial metrics have been used for assessment of the technology substitution in the nuclear industry in India, primarily by comparing the levelised costs of onsite hydrogen generation in small generators …
Published in International Journal of Chemical Engineering and Processing · Vol. 6, Issue 1, 2020 · pp. 14–26 Read article
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A Review on Waste Bakelite as Replacement Partially Over Coarse Aggregate in Concrete Mix
Abstract: Various components in India are made up of Bakelite. Saffron Global Dumping of waste Bakelite through landfill is not allowed due to it effect on soil mass and open burning is not allow because of the emission of harmful gases which cause air pollution. A large space of storehouse requires to store large amount of area for keeping waste Bakelite which becomes management problem of waste. Despite managing waste Bakelite …
Published in International Journal of Concrete Technology · Vol. 9, Issue 2, 2023 · pp. 8–13 Read article
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Enhancing Concrete Durability through Partial Replacement of Coarse Aggregate with Recycled Plastic Granules
Abstract: This research study aims to explore and present the practical application of plastic granules as a substitute for coarse aggregate in the production of concrete cubes and cylinders. The concrete specimens, comprising various percentages of plastic granules (0%, 5%, 10%, 15%, 20%, and 25%), were manually cast and then subjected to empirical tests to evaluate their split tension and compression strengths. Surprisingly, the study found that the compressive and split …
Published in International Journal of Structural Engineering and Analysis · Vol. 9, Issue 1, 2023 · pp. 38–47 Read article