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5 articles for “NSAIDs”
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Postoperative Pain Management: Understanding the Role of NSAIDs and Analgesics
Abstract: Postoperative pain management is a critical aspect of clinical care, with a significant impact on patient recovery and quality of life. Among the pharmacological options available, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and acetaminophen (paracetamol) are widely utilized due to their distinct chemical properties and mechanisms of action. This study aims to evaluate and compare the efficacy of intravenous paracetamol (C₈H₉NO₂) and diclofenac (C₁₄H₁₁Cl₂NO₂) in postoperative analgesia, focusing on their pharmacokinetic profiles, …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 1, 2026 · pp. 36–42 Read article
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A Comparative Study of Intravenous Paracetamol and Intravenous Diclofenac for Post-operative Pain Relief
Abstract: Despite advancements reducing mortality rates, adverse effects such as pain, nausea, and vomiting remain prevalent and can hinder recovery. Pain is now considered the fifth vital sign, as defined by the International Association for the Study of Pain, and inadequate pain management can result in prolonged hospital stays, increased drug use, and delayed recovery. Effective postoperative pain control is crucial in preventing respiratory complications and facilitating early discharge and return …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 50–56 Read article
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Sensitive Spectrophotometric and Flame Photometric Methods for Determination of Diclofenac Sodium in Pharmaceuticals
Abstract: Diclofenac sodium (DFS) is a non-steroidal anti-inflammatory drug (NSAID). Two new analytical methods have been developed for the assay of DFS in its pure form, tablets and injections. Spectrophotometric method is based on the oxidation of drug with known excess of cerium(IV) and oxidation of methyl orange (MO) by residual oxidant and measurement of absorbance of unreacted MO at 470 nm. Flame photometric method is based on the measurement of …
Published in International Journal of Analytical and Applied Chemistry · Vol. 2, Issue 2, 2016 · pp. 1–10 Read article
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Advance in the Synthesis of Oxadiazole Based Heterocyclic Compound
Abstract: The five members of the heterocyclic ring 1,3,4-oxadiazole are necessary for the production of strong bioactive molecules. Numerous pharmacological effects, including anti-inflammatory, antibacterial, anticancer, antitubercular, anticonvulsant, anti-HIV, hypoglycemic, and antioxidant qualities, are exhibited by this intriguing class of chemicals. We have created four novel 1,3,4-oxadiazole compounds in the continuing study, which are sourced from the NSAID Ibuprofen. Melting point analysis and TLC were used to verify the compounds' purity. Open …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 9, Issue 2, 2023 · pp. 10–15 Read article
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Abnormal Immune Response; Autoimmune Diseases: A Critical Review
Abstract: The immune system is a complex organization within the body that is designed normally to “seek and destroy” invaders of the body, including infectious agents. There are at least 80 types of autoimmune diseases. When you have an autoimmune disorder, your immune system does not distinguish between healthy tissue and antigens. As a result, the body sets off a reaction that destroys normal tissues too. Immune deficiency diseases decrease the …
Published in International Journal of Immunological Nursing · Vol. 4, Issue 1, 2018 · pp. 21–26 Read article