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23 articles for “NMR”
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Major Analytical Problems in Current Pharmaceutical Drug Products
Abstract: Substances of pharmaceutical drug products go through thorough analyses to check the safety, efficacy as well as the quality of the final product. There are a number of shortcomings even though much has been done in the analytical methods used in recalls. Such challenges are those concerning method validation, sensitivity, specificity, reproducibility, and regulation. This article on major analytical problems in current pharmaceutical drug products outlines major limitations in the …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 29–39 Read article
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Isolation and Characterization of Alkaloidsfrom Ancistrocladus Heyneanus Leaves: A Phytochemical Study
Abstract: Leaves of Ancistrocladus heyneanus were collected from the forest of the Matheran hills of Maharashtra. From these leaves, alkaloids were extracted using dichloromethane, and two new monomeric Naphthyl-iso-quinoline alkaloids, Youndamine A and Ancistrocline were isolated using TLC and HPLC. HPLC/MS and NMR further identified the patient. The present study involves the collection and chemical investigation of the leaves of Ancistrocladus heyneanus, a plant species found in the forested regions of …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 2, 2024 · pp. 7–20 Read article
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Reactivity of Niobium(V) ComplexTowards Hydroxamate Ligands
Abstract: A niobium(V) complex with the composition [NbCl(OC₆H₄CH(CH₃)₂-2)₄] was synthesized by reacting niobium pentachloride with four equivalents of 2-isopropylphenol in carbon tetrachloride as a solvent, yielding the product in good quantity. The complex was characterized using elemental analysis, molar conductance measurements, IR spectroscopy, ¹H and ¹³C NMR spectroscopy, and mass spectrometry. Spectroscopic results indicate that the complex exists in a dimeric form, with bridging occurring through isopropylphenoxo ligands. X-ray diffraction analysis …
Published in International Journal of Energetic Materials · Vol. 12, Issue 1, 2026 · pp. 1–6 Read article
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Synthesis and Biological Evaluation of a Novel Schiff Base Ligand [(E)-2,4-Dichloro-6-(1-((4-Fluorophenyl) iminoethyl)phenol] and Its Metal Complexes
Abstract: The study involved the synthesis and characterization of a novel bidentate Schiff base ligand, [(E)-2,4-dichloro-6-(1-((4-fluorophenyl) iminoethyl) phenol)], derived from 1-(3,5-dichloro-2-hydroxyphenyl) ethanone and 4-fluoroaniline. Transition metal salts (Co (II), Cu (II), Fe (II), Zn (II), Ni (II), Mn (II), Ag (II), Cd (II), Hg (II), and Pd (II)) were used to synthesize metal complexes. The chemicals used were of analytical grade, and solvents were distilled before use. Characterization involved UV, IR, …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 1, 2024 · pp. 26–35 Read article
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Synthesis of 2-(2,3-dichlorophenyl)-5-(substituted)-1,3,4-Oxadiazole Microcrystals by Solvothermal Method and Assessment of in vitroAntibacterial with Docking and in vivo Larvicidal Efficiency with Comprehensive Toxicological Studies
Abstract: 2,5-Disubstituted 1,3,4-oxadiazole compounds are among the most beneficial organic molecules of biological importance. In the current research, a new series of 2-(2,3-dichlorophenyl)-5-(substituted)-1,3,4-oxadiazole compounds have been synthesized solvothermally from derivatives of2,3-dichloro-N'-(substituted)benzohydrazide and Chloramine-T as an oxidizing agent using autoclave with good yield. The obtained products are micro-sized (5µm–20µm) crystals confirmed through SEM. The structures of synthesized compounds were confirmed through IR, 1H-NMR, 13C-NMR, mass Spectroscopy, Elementary analysis. Molecular docking study shows …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 6, Issue 1, 2020 · pp. 29–44 Read article
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Synthesis, Structural Elucidation, and Antimicrobial Screening of a Cobalt (II) Coordination Compound Derived from a Thiophene-Containing Schiff Base
Abstract: Abstract An N, O-chelating azomethine Schiff base ligand (HL), chemically identified as 2-{[(thiophen-2-yl) methylidene] amino} benzoic acid, was synthesized by an equimolar condensation reaction between thiophene-2-carbaldehyde and anthranilic acid in absolute ethanol in the presence of a catalytic amount of acetic acid. The corresponding cobalt (II) complex, formulated as [Co(L)₂] · 2H₂O, was prepared by refluxing two equivalents of the ligand with one equivalent of cobalt (II) acetate tetrahydrate in …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 1–7 Read article
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Synthesis and Evaluation of Antifungal Properties of 2-((4-((6phenylimidazo[2,1-b][1,3,4]thiadiazole-2-yl)methoxy)phenoxy)methyl)-6-phenylimidazo[2,1-b][1,3,4] thiadiazole Derived from Hydroquinone
Abstract: Thiadiazole, a heterocyclic core, has garnered significant interest from chemists seeking novel therapeutic agents. The synthetic route for the target compounds is depicted in Scheme 1. The compounds were synthesized with favorable yields through the condensation of hydroquinone with various organic reagents. They underwent physical characterization and were analyzed using spectroscopic methods, including infrared (FTIR) and NMR (1H, 13C) spectroscopy. The FT-IR spectrum of the product exhibited a ν(C=N) absorption …
Published in International Journal of Environmental Chemistry · Vol. 12, Issue 1, 2026 · pp. 76–82 Read article
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Study of the Effect of SLS Loading on the One-Pot Synthesis of Substituted Piperidines
Abstract: Piperidine derivatives represent a vital class of nitrogen-containing heterocycles with extensive pharmacological and industrial significance. Their synthesis has garnered considerable interest due to their presence in numerous bioactive molecules, including drugs with CNS activity, analgesic properties, and antimicrobial effects. Traditional multi-step synthetic pathways are often time-consuming and resource-intensive. To address this, one-pot multicomponent reactions (MCRs) have emerged as an efficient and eco-friendly alternative, allowing for the rapid construction of complex …
Published in International Journal of Green Chemistry · Vol. 12, Issue 1, 2026 · pp. 1–9 Read article
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Reactor-Made Polypropylene for 3D Printing: A Low-Crystallinity Approach
Abstract: 3D printing is technology that enables the complex structure, which is difficult in conventional technique. However, relatively slow manufacturing process and using of limited polymeric material leads to attention of scientist towards newer cost-effective material and technology. In this study, we overcome this issue by synthesizing reactor-made polypropylene (mPP) using Dimethylsilylene-(cyclopentadienyl) (fluorenyl)-zirconium-dichloride metallocene catalyst. The polymerization process was systematically optimized by varying Al/Zr molar ratios, catalyst concentrations, and temperatures to …
Published in International Journal of Polymer Science and Engineering · Vol. 11, Issue 2, 2025 · pp. 1–17 Read article
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Synthesis and Antifungal Activity of Some Bis-1,4-(3-Mercapto-5-Oxymethyl-1,2,4-Triazole-5-yl) Benzene & Bis-1,4-(5-Amino-2-Oxymethyl-1,3,4-Thiadiazole-2-yl) Benzene
Abstract: Heterocyclic compounds are well known for their pharmacological application. Among all N-containing heterocyclic compounds, triazole emerges superior application. Triazole have two core structures 1,2,4-triazole and 1,2,3-triazoles. They both can give a broad range of substitutions with their structures, due to these characteristics, they have significant biological applications. They are also important in organocatalysis, agrochemicals, and material science. We aim to explore suitable molecular modifications in thiadiazole and triazole derivatives to …
Published in International Journal of Agrochemistry · Vol. 11, Issue 2, 2025 · pp. 9–15 Read article
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First Ever Experimental Evidence of Nanoyeast Fermenting Glucose
Abstract: In one of the earliest attempts, nanoyeast (Saccharomyces cerevisiae) particles were supported on an exotic and novel support[CD1] , namely, silica gel. The presence of nanoparticles of yeast with size as small as 161 nm was reported. Nanoyeast buds of very small size namely 41 nm were also observed in the HR SEM. Analogous to the nanoparticles in the chemical world, size reduction of microorganisms with commercial relevance like, yeast, …
Published in International Journal of Energetic Materials · Vol. 10, Issue 2, 2024 · pp. 1–6 Read article
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Commercial Scale Quantification of Lignin
Abstract: Lignin, an aromatic biopolymer, in the terrestrial lignocellulosic biomass constitutes the single largest and sustainable source of biofuels and biochemicals. The recalcitrant nature of lignin is a hindrance to its chemical or biochemical conversion. Moreover, its insolubility in water too is a major challenge in its quantification which is a necessary step prior to and after its conversion. Though there are celebrated quantification methods like the classical Klason lignin method …
Published in International Journal of Environmental Chemistry · Vol. 11, Issue 2, 2025 · pp. 20–25 Read article
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Heterocyclic Oxadiazole Derivatives Through Various Spectroscopic Techniques as UV, IR.
Abstract: The study focuses on the synthesis, characterization, and analysis of heterocyclic oxadiazole derivatives using various spectroscopic techniques, including UV-visible (UV-Vis) spectroscopy and infrared (IR) spectroscopy. Oxadiazoles are a type of five-membered heterocyclic compounds with nitrogen and oxygen atoms. They are important in medical chemistry and materials research and show a wide range of biological activity. The synthesized oxadiazole derivatives were characterized through UV-Vis spectroscopy to investigate their electronic transitions and …
Published in International Journal of Analytical and Applied Chemistry · Vol. 10, Issue 1, 2024 · pp. 1–8 Read article
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A Study on the Properties of Methyl Esters of Camelina Sativa Oil
Abstract: The depletion of fossil fuel and the pollution created due to the combustion of fossil fuels created an awareness to find an alternative to fossil fuels. In this present work, the focus is on to utilize the camelina sativa seed to produce oil and the same is trans-esterified to biodiesel and in this connection a detailed analysis has been done. Biodiesel is produced by transesterification of neat Camelina Sativa oil. …
Published in International Journal of Green Chemistry · Vol. 4, Issue 1, 2018 · pp. 1–6 Read article
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Turn-On” Fluorescence Sensing of Bilirubin Using Water-Soluble Conjugated Polymer
Abstract: Early detection of bilirubin is important to detect jaundice and hepatitis disease at the early stage. Currently, there is no fast method available to detect bilirubin level directly in the presence of crucial interference. This report presents a novel water-soluble poly(fluorenes-alt-benzothiadiazole) for turnon sensing of bilirubin in water and human blood serum. The probe is the water-soluble conjugated polymer poly(fluorenes-alt-benzothiadiazole) functionalized with a D-glucuronic acid named PF-BTGlcA. D-glucuronic acid acts …
Published in International Journal of Analytical and Applied Chemistry · Vol. 7, Issue 2, 2021 · pp. 13–20 Read article
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Cassia Fistula Leaf and Flower Extract and their Antibacterial Activity: A Comparative Study
Abstract: Overwhelming side effects of synthetic drugs has attracted researchers for the search and use of herbal drugs. Neem and Curcumin are very widely studied and research is still going on these species. However, Cassia Fistula, is one such plant which has various medicinal values and is less studied. Thus, the present investigation studies the extraction of leaf and flower constituents and the extract has been characterized by FTIR and NMR …
Published in International Journal of Chemical Engineering and Processing · Vol. 5, Issue 1, 2019 · pp. 1–10 Read article
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Preparation and Characterisation of the Schiff’s Base Complex [Pt(dpq)Cl2]
Abstract: Preparation of platinum complex [Pt(dpq)Cl2] and characterization of the complex by IR, UV, CHN and NMR techniques. DPQ ligand is obtained by 1,10 phenanthroline made react with NaBr, nitrating mixture followed by ethylenediamine in ethanol. Keywords: DPQ, intercalator, platinum complex, Schiff’s base
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 1, Issue 2, 2015 Read article
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Synthesis, Spectral characterization and biocidal activities of Triphenyl antimony (V) halide and methoxide complexes
Abstract: The schiff base ligands N-mono(salicyclidene)-σ-phenylenediamine (spdH) and N-mono(2-hydroxy-1-naphthalidene)-σ-phenylenediamine (hnpdH) and their triorganoantimony (V) complexes were synthesized by conventional method, were characterized by UV, IR and 1H NMR spectral studies which proposed that in the complexes of the ligands spdH and hnpdH, antimony is seven coordinated and in sp3d3 hybridization state with pentagonal bipyramidal geometry. Keywords: halide, methoxide complexes, triphenylantimony (V)
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 3, Issue 1, 2017 Read article
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Anti-tubercular activity of dioxo molybdenum (VI) metal complexes of 2-((E)-(1,5-dimethyl-2-phenyl-3-((Z)-(quinoline-8-ylimino)methyl)-2,3-dihydro-1H-pyrazole-4-ylimino)methyl)phenol
Abstract: Dioxomolybdenum(VI) complexes tetradentate ligand 2-((E)-(1,5-dimethyl-2-phenyl-3-((Z)-(quinoline-8-ylimino)methyl)-2,3-dihydro-1H-pyrazole-4-ylimino)methyl)phenol was synthesized by conventional method The ligands and their MoO22+ complexes have been characterized on the basis of elemental analysis, electronic. I.R., 1H and 13C-NMR spectral method, by their spectral studies, octahedral geometry of the complex has been proposed. On evaluation of in-vitro antitubercular activity of the ligand and dioxo Mo(VI) metal complex found that complex is more potent antitubercular agent than ligand. Keywords: anti-tubercular …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 3, Issue 1, 2017 Read article
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Synthesis, characterization of Schiff base and its pH metrically studies of transition metal complexes of N'-(3, 4-dihydroxybenzylidene) isonicotinohydrazide.
Abstract: Schiff reaction is one of the versatile reaction widely used in organic synthesis focused on the discovery & development of isoniazide Schiff base derivative N’(3,4-Dihydroxy benzylidene isonicotinohydrazide) have been reported in presence of 0.01g molecular iodine catalyst stirring give fast product & good yield. The synthesized compound is characterized by FTIR & H-NMR analysis. For the development of coordination chemistry Schiff base & metal ion having played most important role, …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 6, Issue 2, 2020 · pp. 39–47 Read article