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80 articles for “Discoveries”
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Serendipitous Medicines-Discoveries by Chance
Abstract: Discovery is nothing but the art of finding something. In the medical history, number of discoveries happened by chance. These happy accidental discoveries are well known as serendipity, a word coined by Horace Walpore. Serendipity is a pleasant surprise of finding a particularly useful information while not looking for it. There is interesting well known serendipitous drug discoveries in medical science such as penicillin, cephalosporin, aspirin, nitrous oxide, and sildenafil …
Published in International Journal of Composite and Constituent Materials · Vol. 7, Issue 2, 2021 · pp. 12–16 Read article
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Recent Advances in Fused Heterocyclic Pyridine Compounds for Bioactive Anti-Inflammatory Drug Discovery
Abstract: Heterocyclic compounds, particularly those fused with pyridine rings, have emerged as promising candidates in the search for novel bioactive agents with anti-inflammatory properties. This review highlights recent advances in the discovery and development of fused heterocyclic pyridine compounds as potential anti-inflammatory drugs. The unique structural properties of fused heterocycles contribute to their ability to modulate key inflammatory pathways. By targeting specific molecular targets involved in inflammation, such as cytokines, enzymes, …
Published in International Journal of Chemical Separation Technology · Vol. 10, Issue 1, 2024 · pp. 1–7 Read article
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Discovery of Materials through Applied Machine Learning and General Machine Learning Architecture
Abstract: Advances in artificial intelligence technologies, especially machine learning, have generated possibilities in the material sciences to facilitate material exploration and to achieve a profound understanding of the relationship between the constituent elements of the material and the properties represented by the material. The application of machine learning to the exploration of experimental materials is sluggish due to the monetary and temporal costs of experimental data, however parallel methods, such as …
Published in International Journal of Analog Integrated Circuits · Vol. 6, Issue 2, 2020 · pp. 48–57 Read article
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Tools and Concepts for Building A Collaborative Project Discovery and Development Platform: A Literature Review
Abstract: Collaborative project platforms have become indispensable in modern project management, especially with the rise of remote work, accentuated by the COVID-19 pandemic. This literature review synthesizes recent studies to explore the dynamics of collaborative project platforms, focusing on tool choices, usage patterns, and challenges. Organizations need to be ready to take on the obstacles that come with implementing projects. This study collects information on the objectives and issues faced by …
Published in International Journal of Digital Communication and Analog Signals · Vol. 10, Issue 1, 2024 · pp. 13–18 Read article
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Trends and Latest Developments in Industrial Biotechnology
Abstract: Microbial fermentations are used to produce a variety of goods in a sustainable manner. Because of the growing trend in the food industry toward plant-based foods and meat and dairy product substitutes, microbial fermentation will play an increasingly important role in this sector, as it will enable the production of valuable foods and food ingredients in a sustainable and scalable manner. Microbial fermentation will also be employed to improve and …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 8, Issue 1, 2022 · pp. 24–27 Read article
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Review in Dapsone and Sulfa Derivatives with Their Applications in (Fertilizer, Agrochemical, Industrial, Biochemical) Fields
Abstract: Dapsone structure discovered in the early twentieth century, German researcher Paul Ehrlich was acquiring notions of selective toxicity established fundamentally on the ability of specific dyes to destroy microorganisms. Gerhard Domagk was later awarded a Nobel Prize for his efforts, achieving a breakthrough in 1932 with the discovery of the antiseptic ingredient Prontosil inflamed (actinodin sulfonamide). Further inquiry of the chemical factors involved opened the technique for sulfa structures and …
Published in International Journal of Agrochemistry · Vol. 12, Issue 1, 2026 · pp. 11–19 Read article
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Innovative Approaches to Molecular Synthesis for Drug Development
Abstract: The rapidly evolving field of drug development continually seeks innovative methodologies to enhance the efficiency, specificity, and scalability of molecular synthesis. This paper explores recent advancements in synthetic chemistry, focusing on techniques that have shown significant promise in addressing the challenges faced in drug discovery and development. Automated Synthesis: The advent of machine learning and artificial intelligence (AI) in synthetic chemistry has led to the development of automated synthesis platforms. …
Published in International Journal of Chemical Engineering and Processing · Vol. 10, Issue 2, 2024 · pp. 9–14 Read article
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Biotechnological Advances in Improving Abiotic Stress Tolerance in Jute (Corchorus spp.): Genomic and Functional Insights
Abstract: Jute (Corchoruscapsularis and C. olitorius) is an economically significant natural bast fiber crop, particularly in Bangladesh and South Asia that faces severe constraints from salinity and waterlogging due to climate change and coastal inundation. Despite its agricultural importance, jute has historically lacked genomic resources for molecular improvement. Recent release of high‑quality reference genomes, coupled with transcriptomics and functional genomics, has enabled identification of stress‑responsive genes and regulatory networks. This review …
Published in International Journal of Plant Biotechnology · Vol. 12, Issue 1, 2026 · pp. 25–30 Read article
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Molecular Docking of Catharanthus Roseus Bioactive Compounds of Targetinging Bovine Leukaemia Virus
Abstract: Therapeutic potential of Catharanthus roseus bioactive compounds as the 4PHO protein inhibitors, a pathogenetic determinative factor of BLV. This work describes the use of computational drug discovery approaches in estimating the interactions conducted between 40 phytocompounds of Catharanthus roseus and the 4PHO protein. Our work has determined the presence of Pamoic acid and Vindolinine hydrochloride as the optimal choice here. Pharmacokinetic screening exhibited drug-like properties to both the highly absorbed …
Published in International Journal of Animal Biotechnology and Applications · Vol. 11, Issue 2, 2025 · pp. 19–31 Read article
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Brief Introduction to Medicinal Chemistry
Abstract: Medicinal chemistry is an interdisciplinary scientific field of chemistry which combines the applied and basic sciences. In simple words, medicinal chemistry is an interwoven science that combines the basics of chemistry, pharmacy, and drug discovery and designing. It comprises the discovery, development, identification, and interpretation of the mode of action of biologically active molecules and compounds at molecular level.
Published in International Journal of Analytical and Applied Chemistry · Vol. 2, Issue 2, 2016 · pp. 38–39 Read article
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Face Recognition and Identification Using Computer Vision
Abstract: ABSTRACT In practice, identification of criminal in India is done through thumbprint identification. However, this type of identification has many constraints. Our face recognition poses to be able to detect face and recognize face automatically. Nowadays, face recognition systems use biometric for many security applications. This technique uses an image-based approach toward artificial intelligence by removing redundant data from face images through image compression using computer vision that compares a …
Published in International Journal of Image Processing and Pattern Recognition · Vol. 5, Issue 1, 2019 · pp. 6–10 Read article
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Review of Feature Selection Methods and Semi Supervised Feature Selection Algorithms for Classification
Abstract: Current evolution in technology has resulted in tremendous growth of data with respect to dimensionality and sample size. Knowledge discovery from these high dimensional data are becoming cumbersome. Though powerful machine learning algorithms are prevalent, noisy data, imperfect sensing and collection of data leads to poor and defective knowledge discovery. Noise and redundant features cannot be circumvented due to which data collection process is biased. Dimensionality reduction techniques namely feature …
Published in International Journal of Software Computing and Testing · Vol. 6, Issue 1, 2020 · pp. 39–51 Read article
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Vehicle Detection Using Image Processing
Abstract: Vehicle discovery and arrangement of vehicles assume a significant job in dynamic with the end goal of traffic-control and the executives. Right now propose a novel and productive calculation dependent on picture preparing utilizing aeronautical cameras for vehicle recognition and order-particularly in parkways. The calculation is basically founded on an arrangement of Edge-base techniques applied on a picture taken by sensing device of a street fragment. Calculation additionally utilizes thresholding, …
Published in International Journal of Analog Integrated Circuits · Vol. 7, Issue 1, 2021 · pp. 33–38 Read article
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Melanoma’s Nemesis: Assessing the Pharmacological Impact of Curcumin and its Analogues as Inhibitors of Identified Biomarkers Via Network Pharmacology
Abstract: Objectives: Since the advent of next-generation sequencing, melanoma has been recognized as an immensely heterogeneous disease, leading to the discovery of numerous underlying genetic drivers over time. Bioinformatic and machine learning analyses have become increasingly prevalent in risk stratifying melanoma patients with high accuracy, leveraging genetic, clinical, and histopathological inputs. Via various research curcumin has been identified and also shown therapeutic efficacy in Melanoma. In order to reveal the interactions …
Published in International Journal of Applied Nanotechnology · Vol. 9, Issue 1, 2023 · pp. 33–44 Read article
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Cryogenic Electron Microscopy Reveals Conformational Dynamics and Catalytic Mechanisms of Human Fatty Acid Synthase in De Novo Lipid Biosynthesis
Abstract: Fatty acid synthase (FASN) is a multifunctional homodimeric enzyme central to de novo fatty acid synthesis in mammals. Recent cryogenic electron microscopy (cryo-EM) studies have illuminated the structural basis of FASN catalysis, revealing multiple conformational states throughout the synthesis cycle. These findings show that the acyl carrier protein (ACP) domain dynamically shuttles substrates between spatially separated active sites, while the condensing and modifying regions remain structurally stable. In contrast to …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 2, 2026 · pp. 8–25 Read article
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Intelligent Data Analytics on Cloud Infrastructure:Real-Time Insights and Managed Service Models
Abstract: This paper examines the integration of advanced data analytics and machine learning within modern cloud infrastructure, highlighting how organizations can transform large volumes of unstructured data into actionable business insights that drive competitive advantage. Cloud platforms leverage scalability and elasticity to efficiently process and analyze massive datasets in real time, allowing enterprises to identify hidden patterns, detect operational anomalies early, and generate accurate forecasts of future outcomes. A key factor …
Published in International Journal of Distributed Computing and Technology · Vol. 12, Issue 1, 2026 · pp. 36–46 Read article
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Advances in Applied Chemistry: From Electrochemical Biosensors and Gas Sensing to Sustainable Remediation and Nanofluid Engineering
Abstract: Applied chemistry acts as a crucial link between fundamental molecular science and practical technological innovation. It transforms theoretical knowledge into real-world applications that address challenges in healthcare, environment, and industry. This review highlights recent advancements in electrochemical biosensors, which offer rapid and sensitive diagnostic capabilities, along with modern gas detection technologies designed for improved safety and environmental monitoring. Significant attention is given to environmental remediation, particularly the use of activated …
Published in International Journal of Analytical and Applied Chemistry · Vol. 12, Issue 1, 2026 · pp. 20–25 Read article
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Transportable Water and Air Quality Monitoring Equipment Karishma
Abstract: The purpose of this article is to provide a broad summary of recent discoveries, identify important constraints, and suggest future lines of inquiry. In recent years, pollution has surpassed the environment's bearing capacity. There hasn't been much progress despite the installation of multiple pollution-control initiatives. Natural resources are occasionally exploited by unavoidable waste discharges, despite our government's best attempts to safeguard them. For instance, the water-intensive and polluting sectors of …
Published in International Journal of Environmental Chemistry · Vol. 12, Issue 1, 2026 Read article
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The Awesome Power of Microwaves: More than Heating Food
Abstract: An essential part of contemporary technology is microwave energy, a form of electromagnetic radiation having wavelengths between one metre and one millimetre. Its uses extend well beyond the kitchen, even though it is usually associated with cooking. This article overviews basic concepts of microwave energy, the interaction with materials and the generation of heat by dielectric heating. It also shows a range of applications including telecommunications, radar, medical treatments and …
Published in International Journal of Microwave Engineering and Technology · Vol. 12, Issue 1, 2026 · pp. 35–39 Read article
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An Overview on AI in Thermal Behaviour of Polymers
Abstract: The integration of Artificial Intelligence (AI) and Machine Learning (ML) into the thermalanalysis of polymers and composite materials has transitioned from experimental curiosity to acornerstone of material science. By replacing costly and time-consuming trial-and-errorlaboratory testing with predictive modeling, AI is accelerating the development of advancedthermal interface materials, fire-retardant polymers, and aerospace-grade composites. Theprediction and optimization of the thermal behavior of polymers and composite materialsrepresent a cornerstone of modern materials science, …
Published in International Journal of Composite and Constituent Materials · Vol. 12, Issue 1, 2026 · pp. 12–16 Read article