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2 articles for “COX inhibition”
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A Comparative Study of Intravenous Paracetamol and Intravenous Diclofenac for Post-operative Pain Relief
Abstract: Despite advancements reducing mortality rates, adverse effects such as pain, nausea, and vomiting remain prevalent and can hinder recovery. Pain is now considered the fifth vital sign, as defined by the International Association for the Study of Pain, and inadequate pain management can result in prolonged hospital stays, increased drug use, and delayed recovery. Effective postoperative pain control is crucial in preventing respiratory complications and facilitating early discharge and return …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 1, 2025 · pp. 50–56 Read article
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Postoperative Pain Management: Understanding the Role of NSAIDs and Analgesics
Abstract: Postoperative pain management is a critical aspect of clinical care, with a significant impact on patient recovery and quality of life. Among the pharmacological options available, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and acetaminophen (paracetamol) are widely utilized due to their distinct chemical properties and mechanisms of action. This study aims to evaluate and compare the efficacy of intravenous paracetamol (C₈H₉NO₂) and diclofenac (C₁₄H₁₁Cl₂NO₂) in postoperative analgesia, focusing on their pharmacokinetic profiles, …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 1, 2026 · pp. 36–42 Read article