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7 articles for “Apoptosis”
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Investigation of 2, 4-D Hepatotoxicity and Lepidium sativum Antitoxicity on Rat Tissue using FT-IR Spectroscopy
Abstract: Pesticides have been proven to induce various toxicities in animals, plants and humans. The current study aimed to apply FTIR spectroscopy for the investigation of the antitoxic effect of the medicinal plant Lepidium sativum (LS) against the pesticide 2, 4-dichlorophenoxyacetic acid (2, 4-D) hepatotoxicity. Twelve male albino Wister rats were divided into four groups (control, protective, curative and LS only) and were treated for 4 weeks. Results indicated that the …
Published in International Journal of Animal Biotechnology and Applications · Vol. 6, Issue 1, 2020 · pp. 17–29 Read article
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Biosynthesis of silver nanoparticles using Zingiber officinalae and Evaluation of cervical cancer activity
Abstract: This research focused on evaluating the potential anti-cervical cancer properties of silver nanoparticles (AgNPs) that were synthesized using an aqueous extract derived from the rhizome of Zingiber officinale (ginger). The synthesized silver nanoparticles (AgNPs) were thoroughly characterized using a range of analytical techniques, including Ultraviolet-Visible (UV-Vis) spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR), and Field Emission Scanning Electron Microscopy (FESEM).Characterization studies revealed that the synthesized silver nanoparticles (AgNPs) exhibited an average …
Published in International journal of Nanobiotechnology · Vol. 11, Issue 2, 2025 · pp. 1–10 Read article
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An Overview on Cannabis and its Medical Applications
Abstract: Today, cannabis plant is raising interest in medical field due to its potential applications, for example, in antitumor drugs, to treat inflammation, cell proliferation, and cell survival. Cannabinoid receptors have a major role in the mechanism of cancer therapy. But in spite of its advantages in medical field, it has some disadvantages also. Due to lack of proper information, it may cause severe side effects. This paper reviews recent work …
Published in International Journal of Plant Biotechnology · Vol. 4, Issue 2, 2018 · pp. 1–5 Read article
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The Impact of Phytohormones on Human Metabolism and Wellbeing
Abstract: Phytohormones, or plant hormones, are vital organic compounds that regulate plant growth, development, and environmental responses. Recent research has shown that phytohormones like auxins, cytokinin, gibberellins, abscisic acid (ABA), ethylene, brassinosteroids, jasmonates, and salicylic acid may also positively impact human metabolism and overall health. Humans are exposed to these hormones primarily through the consumption of fruits, vegetables, and grains, and emerging studies suggest they may influence human metabolic pathways. This …
Published in International Journal of Plant Biotechnology · Vol. 10, Issue 2, 2024 · pp. 37–48 Read article
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Nanomaterials via Green Synthesis: Insights into Biocompatibility and Biotechnological Applications
Abstract: This review critically examines recent advances in the green synthesis of nanomaterials (NMs) and their diverse biological applications, with a focus on antimicrobial, antioxidant, anticancer, and anti-inflammatory properties. The reviewed studies evaluated key characteristics of green-synthesized NMs, including their size, shape, and concentrations, as assessed in both in vitro and in vivo biological models. Compared to traditional chemical methods, green synthesis demonstrated superior efficacy, enhanced biocompatibility, and reduced toxicity. For …
Published in International Journal of Green Chemistry · Vol. 11, Issue 1, 2025 · pp. 1–16 Read article
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Evaluation of Cytotoxic Activity of Cestrum nocturnum Leaves Extract against A549 Cell Line using MTT Assay
Abstract: Cancer remains a major global cause of death, necessitating ongoing research for effective treatments. Traditional herbal medicine is being explored for novel anti-cancer compounds. This study investigates the cytotoxic effects of Cestrum nocturnum ethanolic extract on A549 lung cancer cells, a type of non-small cell lung cancer (NSCLC). NSCLC is a significant health concern in India, affecting even non-smokers. Cestrum nocturnum, known as Night-blooming jasmine, has shown promise in inhibiting …
Published in International Journal of Plant Biotechnology · Vol. 9, Issue 2, 2023 · pp. 29–33 Read article
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Advancement of Poly-(ADP – Ribose) Polymerase (PARP) Inhibitors in Cancer Progression and Treatment
Abstract: DNA repair mechanisms are the most common and potential targets in cancer treatment. PARP enzymes play a crucial role in detection of DNA damage and its repair and also in apoptosis. Detailed knowledge of these mechanisms leads to the development of poly-(ADP-Ribose) polymerase (PARP) inhibitors as vigorous anticancer drugs with specific action. PARP inhibitors can selectivity kill tumours with deficiencies in DNA repair proteins like BRCA1/2, exploiting synthetic lethality concept. …
Published in International Journal of Animal Biotechnology and Applications · Vol. 1, Issue 1, 2015 Read article