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29 articles for “solvent optimization”
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Process Optimization of Copper Phthalocyanine Pigment PB15:3: A Sustainable Solvent Reduction Strategy for Industrial Applications
Abstract: Copper phthalocyanine pigments, particularly PB15:3 (beta-phase), represent cornerstone materials in the global colorants industry with applications spanning automotive coatings, printing inks, and engineering plastics. Conventional synthesis routes for PB15:3 necessitate copious volumes of high-boiling organic solvents – predominantly dimethylaminoethanol (DMAE) and aromatic hydrocarbons – posing significant environmental burdens and economic constraints. This study presents a systematic investigation of solvent quantity optimization in the pigment finishing process of CI Pigment Blue …
Published in International Journal of Polymer Science and Engineering · Vol. 12, Issue 1, 2026 · pp. 21–40 Read article
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Green Solvent Extraction: Sustainable Approaches for Chemical Separation
Abstract: Solvent extraction techniques have advanced significantly as a result of the increased focus on sustainability and environmental responsibility. Traditional organic solvents, while effective in chemical separation processes, often contribute to environmental pollution and pose health risks. In response, researchers have explored greener alternatives that minimize these adverse effects. Compared to traditional procedures, green solvent extraction offers safer and more environmentally friendly solutions by using bio-based solvents, ionic liquids, and deep …
Published in International Journal of Chemical Separation Technology · Vol. 11, Issue 1, 2025 Read article
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Response Surface Methodology in the Optimization of Biodiesel Production from Palm Kernel Oil and Cellobiose by Acid Catalysis in Non-solvent Medium
Abstract: Cellobiose, rich in hydroxyl (OH) functional groups was used in a solventless transesterification process with Palm Kernel Oil (PKO) to produce high-quality biodiesel and glycerol. Response Surface Methodology (RSM) was used to examine the effect of reaction temperature, catalyst concentration, reaction time, and cellobiose: oil ratio to optimize the process parameters for highpurity and yield of consequent biodiesel. The process was an acid-catalyzed transesterification reacton of Palm Kernel Oil and …
Published in International Journal of Green Chemistry · Vol. 9, Issue 1, 2023 · pp. 1–22 Read article
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Liquid-Liquid Extraction Strategies for the Isolation of Bioactive Heterocyclic Compounds
Abstract: Liquid-liquid extraction (LLE) is a widely employed technique for the isolation of bioactive heterocyclic compounds from natural products, fermentation broths, and synthetic mixtures. The efficiency of LLE depends on several factors, including solvent selection, pH manipulation, salting-out effects, and temperature control. Conventional solvent systems, such as water-organic solvent pairs, are commonly used, while advanced strategies, including ionic liquids (ILs), deep eutectic solvents (DESs), ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE), …
Published in International Journal of Chemical Separation Technology · Vol. 11, Issue 1, 2025 Read article
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Studies on Extraction of Total Tannin Content from seeds of Momordica charantia
Abstract: Bitter Gourd is also known as Bitter Melon or Bitter Apple and few other names also, We called it bitter due to its bitter taste as it contain vitamin C. Its scientific name is Momordica charantia. It is a tropical and subtropical fermented beverage which is grown primarily in India and Eastern regions of Asia. The fruit contains a number of important nutrients. It belongs to the family of Cucurbitaceae …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 8, Issue 2, 2022 · pp. 20–26 Read article
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Modelling and Simulation of a Bio-Fermenter for Ethanol Production
Abstract: Industrialization and world population are continuously increasing and this demands high energy. Ethanol is one of the leading bio-fuel in recent years. In this research, mathematical models were developed to monitor, predict and simulate the rate of production of ethanol from the fermentation process of corn. Increase in the ethanol production was observed within the range of 0 >D_S≤0.25 of solvent dilution rate with the optimum value of ethanol concentration …
Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 7, Issue 1, 2021 · pp. 39–50 Read article
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Studies on Extraction of Bioflavonoids from Leaves of Plumeria rubra
Abstract: Plumeria rubra, a tropical flowering plant from the Apocynaceae family, holds notable aesthetic and traditional significance. It is frequently grown in tropical areas as an ornamental shrub or small tree, reaching up to six meters in height. Renowned for its visual appeal, it is especially valued in the creation of leis and other floral arrangements. Although the plant’s sap is toxic, it is recognized for its medicinal and aromatic potential. …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 11, Issue 1, 2025 · pp. 10–16 Read article
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Studies on Extraction, Modelling and Purification of Quercetin from Peel of Allium cepa
Abstract: ABSTRACT Quercetin is an anti-oxidant, which very efficiently scavenges highly reactive biological species such as peroxynitrite and hydroxyl radical. Quercetin belongs to the flavonoid’s family. The present studies on optimization of physico-chemical parameters like effects of different solvents, different solvent percentages, particle size, pH and extraction time for the extraction of quercetin was studied. The highest quercetin concentration for optimized conditions was 38 µg/ml. In the soxhlet extraction process, the …
Published in International Journal of Plant Biotechnology · Vol. 4, Issue 1, 2018 · pp. 3–11 Read article
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Extraction and Purification of Kaempferol from leaves of Azadirichta indica
Abstract: Azadirachta indica, commonly known as neem, It contains phytochemical compounds like phenolic compounds, flavonoids (Quercetin and kaempferol), tannins, gallic acid, nimbosterol, catechin, nimbine, etc. It shows many pharmacological activities like anti-oxidant, anti-cancer, anti-diabetic, anti-inflammatory activities etc. For the extraction of kaempferol from neem leaves, the optimum results were observed for the effects of different solvents, different solvent percentages, particle size, pH and extraction time for the extraction of kaempferol were …
Published in International Journal of Chemical Separation Technology · Vol. 5, Issue 2, 2019 · pp. 26–30 Read article
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Studies on Extraction and Purification of Total Phenolic Content from Seeds of Carica papaya
Abstract: Carica papaya is belongs to Caricaceae family and it contains high content of phenolic compounds and medicinal properties. It shows various pharmacological activities like anti-oxidant, anti-cancer, anti-diabetic, anti-inflammatory, wound healing activities. Here in this research work, for the extraction of TPC from seeds of Carica papaya, the optimum results were observed for the effects of different solvents, solvent percentages, pH, extraction time and particle size for the extraction of TPC …
Published in International Journal of Industrial Biotechnology and Biomaterials · Vol. 6, Issue 2, 2020 · pp. 39–43 Read article
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Extraction of Bioflavonoid from Peel of Citrus sinensis
Abstract: Citrus sinensis is belongs to the Rutaceae family. This is also known as orange fruit and it contains several phytochemicals like phenolic compounds, phenolic acids, bioflavonoids (quercetin, rutin and kaempferol), saponins, carotenoids, citric acid and vitamin C (ascorbic acid). It shows various pharmacological activities like antioxidant activity, anti-inflammatory activity, anti-diabetic activity, anti-cancer activity, wound healing activity etc. This plant control the various disorders in the society. Bioflavonoids also assist in …
Published in International Journal of Chemical Separation Technology · Vol. 7, Issue 1, 2021 · pp. 1–5 Read article
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Comprehensive Manufacturing Processes, Chemical Syntheses, and Mass Balance Analyses for Ten Essential Fungicides in Agrochemical Production
Abstract: This research paper presents a detailed examination of the manufacturing processes for ten key fungicides used in agrochemical applications: Amisulbrom, Azoxystrobin, Benzovindiflupyr, Bixafen, Boscalid, Carboxin, Carpropamid, Cyazofamid, Cyclobutrifluram, and Cyflufenamid. For each fungicide, the synthesis pathways are outlined, including step-by-step chemical reactions, basic chemistry, reactant stoichiometries, and mass calculations based on a standardized production scale of 1000 kg of the final product. Mass balances are provided to account for inputs …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 11, Issue 2, 2026 · pp. 1–21 Read article
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Synthesis, Characterization and Optimization of Essential Oil from Pumpkin Seed
Abstract: The main aim of this research work was extraction, characterization and optimization of essential oil from pumpkin seed, cucurbita pepo variety using ethanol as a solvent. The extraction was carried out by using a Soxhlet, leaching method and oil was separated from solvents by using rotary evaporator. Pumpkin seed was analyzed for proximate analysis and found that moisture content of 5.21 , crude proteins content of 22.50.31%, crude fat content …
Published in International Journal of Chemical Separation Technology · Vol. 7, Issue 1, 2021 · pp. 6–27 Read article
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Synthesis and Characterization of Quinacridone Violet (Pigment Violet 19): Process Optimization and Colorimetric Evaluation
Abstract: Objective: This study focuses on the synthesis and characterization of Quinacridone Violet (Pigment Violet 19), a high-performance organic pigment known for excellent lightfastness and durability. The research aims to optimize the manufacturing process and evaluate the colorimetric properties of the synthesized pigment. Methods: PV 19 was synthesized via a multi-step process involving condensation, oxidation/hydrolysis, and ring closure/cyclization reactions. Two experimental batches (MM#973-A1/B1 and MM#974-A1/B1) were prepared with varying mole ratios …
Published in International Journal of Polymer Science and Engineering · Vol. 12, Issue 1, 2026 · pp. 41–51 Read article
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Design and Optimization of Heterogeneous Catalysts for Green Chemistry Processes
Abstract: The design and optimization of heterogeneous catalysts are critical for advancing green chemistry processes, aiming to minimize environmental impact while maximizing efficiency. This study explores innovative strategies for the development of heterogeneous catalysts that facilitate environmentally benign reactions. By integrating principles of catalyst design, surface science, and reaction engineering, we aim to enhance catalytic performance, selectivity, and stability. Catalyst composition and structure, investigating novel materials, including metal-organic frameworks (MOFs), zeolites, …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 1, 2025 · pp. 42–48 Read article
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Treatment of CO2+NH3 Mixed Waste Gas from Different Sources by Blend Solvents
Abstract: The waste gas from chemical plants, including urea fertilizer plant, contains a large amount of CO2 gas in addition to NH3 gas. New solvents have been studied for use in the absorption of waste gases, but most of them are carried out at specific compositions and flow rates for individual gases. In this paper, a complete conceptual design of the process for separately absorbing CO2 and NH3 gases in a …
Published in International Journal of Chemical Separation Technology · Vol. 10, Issue 2, 2024 · pp. 1–19 Read article
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Technical Insights into the Industrial Synthesis and Production of Ten Prominent Plant Growth Regulator Molecules: Process Flow and Mass Balance Determination
Abstract: Plant Growth Regulators (PGPRs) are indispensable tools in modern agriculture, offering precise control over various aspects of plant development and enhancing crop productivity. While their diverse applications are widely recognized, detailed technical insights into their industrial manufacturing processes, including synthesis routes, process flow, and mass balance, are often limited. This manuscript addresses this gap by presenting a comprehensive technical analysis of the industrial synthesis and production of ten prominent PGPR …
Published in International Journal of Analytical and Applied Chemistry · Vol. 11, Issue 2, 2025 Read article
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Artificial Intelligence for the Art and Science of Separation: Optimizing Chemical Systems
Abstract: Chemical separation processes play a critical role across chemical manufacturing, energy production, pharmaceuticals, and environmental remediation, yet they remain among the most energy-intensive operations in modern industry. Recent advancements in artificial intelligence (AI) offer transformative opportunities to significantly improve the efficiency, selectivity, and sustainability of these systems by leveraging computational power and data-driven insight. This article reviews the emerging integration of machine learning, data-driven modeling, and advanced optimization algorithms with …
Published in International Journal of Chemical Separation Technology · Vol. 11, Issue 2, 2025 · pp. 1–7 Read article
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Continuous Counter-current Liquid–Liquid Extraction in a Packed Column: Experiments and Simulations using Aspen Plus
Abstract: The liquid–liquid two-phase mass transfer in a packed column was examined by varying acetic acid concentrations in the feed, solvent to feed flow rate S/F ratio using random packing. The overall volumetric mass transfer coefficient, percentage extraction, Number of Transfer Units were determined quantitatively. Simulation results were validated with experimental data and optimization of number of stages was done by using Aspen Plus. From the results obtained in the packed …
Published in International Journal of Chemical Engineering and Processing · Vol. 7, Issue 2, 2021 · pp. 1–9 Read article
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Supercritical Fluid Extraction: Mechanisms, Applications, and Recent Developments
Abstract: Supercritical Fluid Extraction (SFE) is an advanced and versatile separation technique that harnesses the unique properties of supercritical fluids (SCFs) to extract a wide variety of compounds from both solid and liquid matrices. Supercritical fluids, which are substances at a temperature and pressure above their critical points, possess both liquid-like density and gas-like viscosity, making them highly effective solvents for extraction processes. This review delves into the underlying mechanisms of …
Published in International Journal of Chemical Separation Technology · Vol. 11, Issue 1, 2025 Read article