International Journal of Applied Nanotechnology
Volume 9, Issue 1 (2023)
Published
Table of contents
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From Fireworks to Rocket Fuel: What to Understand from Solid Propellants
Abstract: Solid propellants are high-energy materials that are used to propel and thrust missile systems and rockets. Despite the fact that they have a long history dating back to the employment of black powder over two millennia, performance gains expectations and the requirement for" insensitive weapons" that are resilient to unintentional ignition have motivated much study and development in the last half-century subjecting to the formation of SRMs engines (main combustion …
Published in International Journal of Applied Nanotechnology · Vol. 9, Issue 1, 2023 · pp. 1–12 Read article
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Machine Learning Bouc-Wen Model for Nano- positioning System
Abstract: Most of the application in present world has taken ‘Nano’ as a part of their near future implementation. In Nano-Positioning System (NPS) the mechanical dynamics are handled at Nano scale. Designing a precisioned NPS is a greater challenge. To have a better hysteresis and better behaviour (Static/Dynamic) the Bouc-Wen model is modified by linearizing. In this work SISO (Sıngle-input Sıngle-Output) and MIMO (Multiple-Input Multiple-Output) models of NPS are designed. In …
Published in International Journal of Applied Nanotechnology · Vol. 9, Issue 1, 2023 · pp. 14–25 Read article
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Recent Developments in Microcantilever-based Biosensors for Detection of Pathogens and Toxins
Abstract: Microcantilever-based biosensors have emerged as a highly promising platform for the rapid, sensitive, and label-free detection of pathogens and toxins. This paper provides an in-depth review of recent advancements in microcantilever biosensor technology, encompassing developments in microcantilever array fabrication, surface functionalization, motion detection methods, and specialized software for sensor system operation and analysis. The focus lies on applications pertaining to the detection of viruses, bacteria, and biological toxins. Additionally, the …
Published in International Journal of Applied Nanotechnology · Vol. 9, Issue 1, 2023 · pp. 26–32 Read article
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Melanoma’s Nemesis: Assessing the Pharmacological Impact of Curcumin and its Analogues as Inhibitors of Identified Biomarkers Via Network Pharmacology
Abstract: Objectives: Since the advent of next-generation sequencing, melanoma has been recognized as an immensely heterogeneous disease, leading to the discovery of numerous underlying genetic drivers over time. Bioinformatic and machine learning analyses have become increasingly prevalent in risk stratifying melanoma patients with high accuracy, leveraging genetic, clinical, and histopathological inputs. Via various research curcumin has been identified and also shown therapeutic efficacy in Melanoma. In order to reveal the interactions …
Published in International Journal of Applied Nanotechnology · Vol. 9, Issue 1, 2023 · pp. 33–44 Read article
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Integrative Network Pharmacology and Molecular Docking Analysis Reveals Potent Inhibition of Ovarian Cancer-Associated Proteins by Curcuma Longa Derivatives
Abstract: Objectives: A network pharmacology approach and molecular docking study were employed to explore how the active ingredients of Curcuma longa interact with protein targets associated with ovarian cancer. The objective was to explore the mechanism of action of these active ingredients. Methods: In this study, a total of 14 derivatives of Curcuma longa were selected to evaluate their binding affinity with specific target proteins (HLA, CDK-41, EGFR, Tumor suppressor p53 …
Published in International Journal of Applied Nanotechnology · Vol. 9, Issue 1, 2023 · pp. 45–67 Read article