Diamond–Blackfan Anaemia (DBA)

R. Deepa

International Journal of Immunological Nursing

Diamond–Blackfan Anaemia (DBA)

R. Deepa

Abstract

In Diamond–Blackfan anaemia (DBA), the bone marrow (soft centre part of most bones) does not make adequate red blood cells (RBC). It is a type of marrow failure disorder. RBC take oxygen from the lungs to all parts of your body. A low level of RBC is called anaemia. In anaemia, the body’s organs may not get sufficient oxygen. How serious anaemia is different from child to child with this illness. It can change or reduce over time. DBA is a genetic disease that influences the body’s ribosomes, which are small cellular structures that play a crucial role in building proteins in the body. Mostly children with DBA have mutations or changes in a ribosomal protein gene, and mutations at least 11 such genes have been linked to DBA. DBA is an eventually life-threatening condition that can be the reason of severe anaemia and other abnormalities.

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Diamond–Blackfan Anaemia (DBA)

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