International Journal of Chemical Synthesis and Chemical Reactions
Volume 10, Issue 1 (2025)
Table of contents
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One-Pot Multicomponent Reactions: A Versatile Approach for Heterocyclic Compound Synthesis
Abstract: Multicomponent reactions (MCRs) represent an efficient and versatile approach in organic synthesis, enabling the formation of complex molecules through a single, one-pot procedure. This methodology is particularly advantageous for the synthesis of heterocyclic compounds that are prevalent in numerous biologically active molecules and pharmaceuticals. The one-pot nature of MCRs allows for the simultaneous combination of three or more reactants, leading to high atom economy, reduced reaction times, and minimized purification …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 1, 2025 · pp. 1–7 Read article
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Synthesis, Characterization and Photoconductive Properties of Antimony Selenium Iodide
Abstract: A shiny needle-shaped polycrystalline chalcogenide compound, SbSeI, was synthesized through a solid-state thermal reaction by combining the constituent elements in a stoichiometric ratio within an evacuated quartz tube at 585°C for 3.5 hours. The resulting compound was characterized using SEM, EDAX, and XRD techniques to confirm its structure and composition. The resistance versus temperature curve revealed the semiconducting nature of the material with a resistivity of 3.5 x 10⁷ Ω-cm …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 1, 2025 · pp. 1–8 Read article
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Synthesis and Evaluation of Antimicrobial Activity of Some Heterocyclic Moieties of Pyrazole Derivatives
Abstract: In a successful trial to synthesize pyrazole derivatives, acetophenone was, first, reacted with phenylhydrazine producing the Schiffs’s base condensation product (E)-1-phenyl-2-(2-phenylethylidene) hydrazine 1. The application of Vilsmeier Haack’s reaction on this product afforded the cyclization product (1,3-diphenyl-1H-pyrazole-4-carbaldehyde 2 as a pyrazole derivative in good yield percentage. The treatment of (1,3-diphenyl-1H-pyrazole-4-carbaldehyde (2) with acetophenone results in the formation of another pyrazole derivative (3), having a chalcone moiety.The chemical structure of newly …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 1, 2025 · pp. 26–36 Read article
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Design and Optimization of Heterogeneous Catalysts for Green Chemistry Processes
Abstract: The design and optimization of heterogeneous catalysts are critical for advancing green chemistry processes, aiming to minimize environmental impact while maximizing efficiency. This study explores innovative strategies for the development of heterogeneous catalysts that facilitate environmentally benign reactions. By integrating principles of catalyst design, surface science, and reaction engineering, we aim to enhance catalytic performance, selectivity, and stability. Catalyst composition and structure, investigating novel materials, including metal-organic frameworks (MOFs), zeolites, …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 1, 2025 · pp. 42–48 Read article
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Doping and Its Impacts on the Properties of ZnO Nanocrystals: A Brief Review
Abstract: Research on zinc oxide (ZnO) has surged in recent years due to its extensive range of applications because its unique physical and chemical properties make it ideal for various uses, including acoustic devices, photocatalysis, pharmaceuticals, light-emitting diodes, solar cells and antibacterial agents. ZnO nanoparticles are particularly notable for their biocompatibility, low toxicity and stability, making them suitable for drug delivery and antiviral applications. The versatility of ZnO has led to …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 10, Issue 1, 2025 · pp. 8–25 Read article