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    Grindstone Chemistry: Facile Green Chemical Approach for the Synthesis of Pyran Scaffolds

    Abstract: Chemical transformations through physical grinding of precursors using mortar and pestle are usually termed as ‘Grindstone Chemistry’. The main feature of this method such as does not require costly equipment, allows solvent and waste-free transformations under mild conditions, and normally involves short reaction time, high product yield and selectivity made this protocol attractive among unconventional synthetic approaches. On the other hand, Pyrans are important heterocyclic structures found applications in various …

    Published in International Journal of Green Chemistry · Vol. 6, Issue 2, 2020 · pp. 30–40 Read article

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