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    Preparation of Beta Lactam Compounds and Study of Thermodynamically Behavior

    Abstract: Several Lactam derivatives have been prepared by condensation reaction of folic acid with (4-chloroacetophenone and 4-hydroxyacetophenone) in ethanol. Then the resultant compounds (1,2) react with another Schiff bases by reacting of 4- bromobenzaldehyde with an amino acid (Phenylalanine, Tryptophan, Tyrosine and Histidine) to give bis-β-lactam rings. The structures of target compounds were characterized by many spectroscopic methods including NMR, FTIR technique and their melting points. The β- lactam derivatives were …

    Published in International journal of Thermodynamics and Chemical Kinetics · Vol. 5, Issue 2, 2019 · pp. 9–15 Read article

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