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Protein Peroxidation: The Covalent Modification of Protein Induced Through Reactive Oxygen Species (ROS) and With Secondary By-products of Oxidative Stress.By Sandhya Pralhad Kinhale, Vitthalrao Bhimasha Khyade
Abstract: The abundance in biological system and high reaction rate constant are making the proteins as major targets for radicals and two-electron oxidants in biological systems. The multiple side-chain and backbone sites are susceptible for highly reactive radical damage. Less reactive species exhibit greater selectivity with reference to the residues targeted and their spatial location. Modified structure may result in the increased side-chain hydrophilicity, side-chain fragmentation and backbone fragmentation, aggregation through …
Published in International Journal of Chemical Separation Technology · Vol. 5, Issue 2, 2019 · pp. 1–25 Read article →