2 publications
-
Published Subscription
Statistical and Artificial Neural Network for the Determination of Thermo-Physical Properties of Fomoditine Drug Using Mixed HydrotropyBy C Jaya Kumar, C. Raja, V. Sampath Kumar, M. Dharmendirakumar
Abstract: The experimental determination of thermo-physical properties of fomoditine drug–mixed hydrotrope concentration mixture is very time consuming as well as tedious process. Any tool helpful in estimation of these properties without experimentation can be of immense utility. In present work, other tools of determination of properties of fomoditine drug–mixed hydrotrope concentration blends were tried. A traditional statistical technique of linear regression (principle of least squares) was used to estimate the specific …
Published in International Journal of Chemical Engineering and Processing · Vol. 1, Issue 2, 2015 · pp. 1–6 Read article →
-
Published Subscription
Solubility Enhancement of Theophylline Drug Using Mixed Solvency ApproachBy C Jaya Kumar, M. Dharmendira Kumar
Abstract: “Solubility enhancement” is one of the difficult tasks that have become a great challenge in formulation development of orally administered drugs having poor aqueous solubility. Poor aqueous solubility of drugs creates significant problems in producing formulations of sufficiently high bioavailability, thereby preventing the effective usage of these drugs. With the introduction of the concept of “mixed-solvency,” it is feasible to increase the solubility of poorly water-soluble drugs in aqueous solutions …
Published in International Journal of Chemical Separation Technology · Vol. 1, Issue 2, 2015 · pp. 1–4 Read article →