12 publications
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Nanostructured Hydroxyapatite: A Biomimetic Revolution in Enamel Regeneration and RemineralizationBy Atul Khajuria, Sukhmeet Kaur Bedi,
Abstract: Background Dental caries and erosive enamel wear remain among the most common chronic conditions worldwide, affecting more than 2 billion people and contributing to pain, tooth loss, and substantial economic costs. Conventional fluoridebased strategies reduce demineralization but do not fully restore enamel microstructure. Source and selection of data We searched MEDLINE, Embase, Scopus, and Cochrane Library for in vitro, in situ, and clinical studies on nanohydroxyapatite (nHAp) used for enamel …
Published in International Journal of Composite and Constituent Materials · Vol. 12, Issue 1, 2026 · pp. 1–11 Read article →
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Spermmediated gene transfer revisited: optimizing delivery, integration, and germline transmissionin large animal modelsBy Atul Khajuria, Ashish Kumar
Abstract: Spermmediated gene transfer (SMGT) exploits the natural role of spermatozoa as DNA vectors to deliver exogenous genetic material to oocytes, potentially enabling economical production of transgenic large animals without complex embryo micromanipulation (1). Early proofofconcept studies established that mammalian sperm can bind, internalize, and protect exogenous DNA, leading to integration, expression, and germline transmission in various species, including pigs (24). Subsequent mechanistic work has challenged the traditional view of sperm …
Published in International Journal of Animal Biotechnology and Applications · Vol. 12, Issue 1, 2026 Read article →
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Enhancing the strength and flexibility of crowns and bridges: advances in materials, design, and nanotechnology.By Sukhmeet Kaur Bedi,, Atul Khajuria
Abstract: The continuous advancement in restorative dentistry has led to the integration of nanotechnology in the fabrication of crowns and bridges, significantly enhancing their mechanical and functional performance. Nano-enhanced materials, including nanoparticle-reinforced resin matrices, nanostructured ceramics, and nano-modified adhesive systems, demonstrate superior properties compared to conventional materials. These improvements are largely attributed to the uniform dispersion of nanoparticles, which enhances filler–matrix bonding, increases surface interaction, and reduces microstructural defects, resulting in …
Published in International journal of Nanobiotechnology · Vol. 12, Issue 1, 2026 · pp. 34–42 Read article →
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Nanoenabled resinbased composites in restorative dentistry: mechanical performance, aesthetic outcomes, and global regulatory considerationsBy Atul Khajuria
Abstract: Resinbased composites are central to contemporary restorative dentistry but remain constrained by polymerization shrinkage, wear and color instability, which compromise longterm restoration success. Nanoenabled resinbased composites (nanocomposites) have been developed to overcome these limitations by incorporating nanosized fillers and engineered nanostructures into conventional resin matrices, thereby enhancing mechanical properties and optical performance. This narrative Review summarises current evidence on the evolution, composition, and mechanisms of nanoenabled resinbased composites; compares their …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 12, Issue 1, 2026 · pp. 39–45 Read article →
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Xerostomia and Salivary Gland Hypofunction: From Pathophysiology to Nanotechnology‑Enabled Regenerative TherapiesBy Atul Khajuria, Sukhmeet Kaur Bedi,
Abstract: Xerostomia, the subjective sensation of oral dryness, is a common yet frequently underrecognized condition with multifactorial etiology and substantial consequences for oral and systemic health. Salivary gland hypofunction underlies many, but not all, cases and may result from medication use, head and neck radiotherapy, autoimmune disease, systemic illnesses, or age-related and hormonal changes. Persistent xerostomia impairs mastication, swallowing, speech, taste, and sleep, and predisposes to dental caries, periodontal disease, oral …
Published in International journal of Nanobiotechnology · Vol. 12, Issue 1, 2026 · pp. 1–27 Read article →
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Nanotechnology-Enabled Non-Invasive Teeth Whitening: Safety,Efficacy, and Regulatory Perspectives with a Focus on India, Asia, and Developed CountriesBy Sukhmeet Kaur Bedi,, Atul Khajuria
Abstract: Demand for tooth whitening is growing worldwide, but conventional peroxide-based bleaching is associated with dentin hypersensitivity, enamel softening, and softtissue irritation, especially under repeated or high-concentration use. Nanotechnology offers a new class of non-invasive whitening strategies that aim to combine esthetic improvement with enamel protection and remineralization. Among these, nanohydroxyapatite (nanoHAP) toothpastes and gels have the most advanced evidence base; in vitro and in situ studies indicate that nanoHAP deposits …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 12, Issue 1, 2026 Read article →
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Nanotechnology-Enabled Non-Invasive Teeth Whitening: Safety, Efficacy, and Regulatory Perspectives with a Focus on India, Asia, and Developed CountriesBy Atul Khajuria, Sukhmeet Kaur Bedi,
Abstract: Demand for tooth whitening is growing worldwide, but conventional peroxide-based bleaching is associated with dentin hypersensitivity, enamel softening, and soft tissue irritation, especially under repeated or high-concentration use. Nanotechnology offers a new class of non-invasive whitening strategies that aim to combine esthetic improvement with enamel protection and remineralization. Among these, nanohydroxyapatite (nanoHAP) toothpastes and gels have the most advanced evidence base; in vitro and in situ studies indicate that nanoHAP …
Published in International Journal of Nanomaterials and Nanostructures · Vol. 12, Issue 1, 2026 Read article →
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Safety, Toxicology, and Regulatory Science of CT Nano‐Contrast Agents in RadiologyBy Atul Khajuria
Abstract: Nanoparticle-based contrast agents for X-ray computed tomography (CT) seek to overcome limitations of conventional iodinated small-molecule media but raise distinctive safety, toxicology, and regulatory science questions. Nano–bio-interactions specific to CT nanocontrast include reticuloendothelial system (RES) uptake, long-term hepatic and splenic retention, size-dependent renal versus hepatobiliary clearance, and potential immunogenicity and genotoxicity, all strongly influenced by particle composition, size, shape, surface charge, and coating chemistry. Robust preclinical evaluation requires harmonized in …
Published in International Journal of Applied Nanotechnology · Vol. 12, Issue 1, 2026 · pp. 36–47 Read article →
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Quantum Dots in Oral Diagnostics and Theranostics: Promise and Preclinical StatusBy Atul Khajuria, Sukhmeet Kaur Bedi,
Abstract: Quantum dots in oral diagnostics and theranostics represent a rapidly evolving, largely preclinical strategy that couples highly sensitive optical imaging with targeted therapeutic delivery in the oral cavity. Their size-dependent emission, high photostability, and broad excitation spectra allow bright, multiplexed visualization of key molecular events in oral potentially malignant disorders and oral squamous cell carcinoma, while surface functionalization with antibodies, peptides, or smallmolecule ligands enables selective binding to dysplastic and …
Published in International Journal of Applied Nanotechnology · Vol. 12, Issue 1, 2026 · pp. 18–25 Read article →
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Prevalence and Risk Factors of Autoimmune Diseases Among Women in Punjab: A Hospital-Based StudyBy J. Samuel KAMANDA, Atul Khajuria, Eric Kwasi Elliason, Stephen Monday
Abstract: Autoimmune diseases (ADs) are a major public health concern, disproportionately affecting women due to hormonal, genetic, and environmental influences. This hospital-based study investigated the prevalence and risk factors of ADs among women in Punjab, India. A total of 800 participants (680 cases, 120 controls) aged ≥18 years were enrolled. Inclusion criteria comprised confirmed AD diagnoses (per standard classification criteria), while exclusion criteria eliminated confounding conditions. Data on demographics, lifestyle, and …
Published in International Journal of Immunological Nursing · Vol. 11, Issue 2, 2025 · pp. 1–7 Read article →
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Biofunctionalized Nanoparticles for Early Detection of Cervical Cancer in Rural North Indian WomenBy Stephen Monday, Atul Khajuria, Eric Kwasi Elliason, Gagan, J. Samuel Kamanda
Abstract: Among the Indian women, cervical cancer is still the second most prevalent cancer and one of the leading causes of cancer death especially in the rural areas where screening and diagnostic facilities are not developed. This study assesses the feasibility, awareness, and acceptability on the use of biofunctionalized nanoparticles for early detection of cervical cancer in women from rural North India. Using a pre-tested structured questionnaire, a community-based cross-sectional survey …
Published in International Journal of Applied Nanotechnology · Vol. 11, Issue 2, 2025 Read article →
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To Assess Radiation Awareness Among Healthcare Workers and Their Approach Toward Radiation ProtectionBy Vaishali Chauhan, Lalita Saini, Atul Khajuria
Abstract: Every healthcare professional, whether directly or indirectly exposed to radiation, needs to be knowledgeable about radiation protection to make sure that the potential risks do not outweigh the advantages of diagnostic imaging. The purpose of this study was to evaluate the healthcare staff at Indus International Hospital in Derabassi’s understanding of radiation protection. Healthcare professionals, including nurses, technicians, doctors, and general duty personnel, participated in a cross-sectional survey. The quantitative …
Published in International Journal of Energetic Materials · Vol. 10, Issue 2, 2024 · pp. 1–6 Read article →