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Synthetic Studies on Fused Benzodiazepines: A Class of Medicinally Privileged HeterocyclesBy Anup K Sasmal
Abstract: 1,4-Benzodiazepine is an important nitrogen heterocyclic scaffold because of its presence in various natural products, drugs and biologically active molecules. Henceforth, it is also known as privileged heterocycle in the field of medicinal to synthetic organic chemistry. Reactions towards the synthesis of five- and six- membered heterocycles are very easy and facile. On the other hand, synthesis of medium ring heterocycles is more difficult because of the thermodynamic limitations. Thus …
Published in International Journal of Chemical Synthesis and Chemical Reactions · Vol. 4, Issue 2, 2018 · pp. 44–59 Read article →